Guida F, Clemente M, Valvano L, Napolitano C
G Chir. 2015 Sep-Oct;36(5):225-30. doi: 10.11138/gchir/2015.36.5.225.
Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy with an estimated worldwide incidence of 0.5-2 per million/year. Complete surgical removal of ACC represents the current treatment of choice for this tumor. A disease-free resection margin (R0) is an important predictor of long-term survival: surgery is demanding and must be performed by a highly experienced surgical team. We report the surgical strategy adopted in a patient with locally advanced ACC and virilization to obtain a R0 resection.
肾上腺皮质癌（ACC）是一种罕见且侵袭性强的内分泌恶性肿瘤，全球估计发病率为每年百万分之0.5 - 2。完整手术切除ACC是目前该肿瘤的首选治疗方法。无病切缘（R0）是长期生存的重要预测指标：手术要求高，必须由经验丰富的手术团队进行。我们报告了一名局部晚期ACC伴男性化患者为实现R0切除所采用的手术策略。
