a Ophthalmology Department , University Hospital of Bellvitge , Barcelona , Spain.
b Ophthalmology Department , Clinica Diagonal , Barcelona , Spain.
Ocul Immunol Inflamm. 2016 Dec;24(6):607-609. doi: 10.3109/09273948.2015.1094094. Epub 2015 Dec 29.
To report a case of bilateral panuveitis with vasculitis, an unusual manifestation of post-streptococcal uveitis syndrome (PSU).
An 8-year-old patient consulted for bilateral red eye following acute tonsillitis. Exploration revealed bilateral anterior uveitis, vitritis, macular edema, and Frosted Branch Angiitis. Given a clinical suspicion of PSU, blood and serology tests were performed to rule out other causes of vasculitis and retinitis.
Serologies came back negative except for highly elevated antistreptolysin-O titers. Topical and oral corticosteroids normalized the patient's visual acuity and clinical findings within a few weeks. A subsequent anterior-only recurrence was successfully resolved with topical treatment.
Although PSU most commonly manifests as anterior uveitis, it may present with involvement of the posterior pole. To achieve a correct diagnosis, clinical suspicion and assessment of antistreptolysin-O titers as well as ruling out other conditions with similar clinical features are the mainstay approaches to diagnosis. Prognosis is generally good.
报告一例伴有血管炎的双眼全葡萄膜炎，这是链球菌后葡萄膜炎综合征（PSU）的一种不常见表现。
一名 8 岁患者因急性扁桃体炎后出现双眼眼红就诊。检查发现双眼前葡萄膜炎、玻璃体炎、黄斑水肿和霜样树枝状血管炎。由于临床怀疑 PSU，进行了血液和血清学检查以排除其他血管炎和视网膜炎的原因。
除抗链球菌溶血素 O 滴度显著升高外，血清学检查结果均为阴性。局部和口服皮质类固醇在数周内使患者的视力和临床发现恢复正常。随后的仅前葡萄膜炎复发经局部治疗成功解决。
尽管 PSU 最常见的表现为前葡萄膜炎，但它也可能累及后极。为了做出正确的诊断，临床怀疑、抗链球菌溶血素 O 滴度评估以及排除具有类似临床特征的其他疾病是诊断的主要方法。预后通常良好。
