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盐与血压:一项社区试验。

Salt and blood pressure: a community trial.

作者信息

Forte J G, Miguel J M, Miguel M J, de Pádua F, Rose G

机构信息

Centro de Estudos de Cardiologia Preventiva, INSA, University Hospital of Santa Maria, Lisbon, Portugal.

出版信息

J Hum Hypertens. 1989 Jun;3(3):179-84.

PMID:2671369
Abstract

The effect of a health education programme on salt reduction and blood pressure was studied in two matched rural communities in Portugal, each of about 800 adult inhabitants. Initial salt intake was high (about 360 mmol/person/day) and 30% of persons were hypertensive (DBP 95 mmHg or above). In the intervention community average blood pressure fell by 3.6/5.0 mmHg at one year and 5.0/5.1 mmHg at two years, due to a general distribution shift. In the control community diastolic pressures remained stable and systolic pressures rose. The difference in trends between the two communities was highly significant. There were also significant correlations within individuals in the intervention community between fall in blood pressure and fall in urinary sodium/creatinine ratio. At least in this high-intake population a fall in salt consumption seems to have caused an important fall in average blood pressure.

摘要

在葡萄牙两个相匹配的农村社区(每个社区约有800名成年居民)研究了一项健康教育计划对减少盐摄入量和血压的影响。初始盐摄入量很高(约360毫摩尔/人/天),30%的人患有高血压(舒张压95毫米汞柱或以上)。在干预社区,由于总体分布变化,平均血压在一年时下降了3.6/5.0毫米汞柱,在两年时下降了5.0/5.1毫米汞柱。在对照社区,舒张压保持稳定,收缩压上升。两个社区之间的趋势差异非常显著。在干预社区中,个体的血压下降与尿钠/肌酐比值下降之间也存在显著相关性。至少在这个高盐摄入人群中,盐摄入量的下降似乎导致了平均血压的显著下降。

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