Department of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA.
Hypertension. 2024 Mar;81(3):510-515. doi: 10.1161/HYPERTENSIONAHA.123.20544. Epub 2023 Aug 29.
The global burden of cardiovascular disease (CVD) continues to grow, as does the incidence of hypertension, one of the most important modifiable risk factors of CVD. Non-pharmacologic, population level interventions are critically needed to halt the hypertension pandemic, but there is an ongoing debate as to whether public policy efforts should focus more on dietary sodium reduction or increasing potassium. In this commentary, we summarize arguments in favor of policy geared towards reduced sodium intake. Recognizing increasing dietary sodium as one of the drivers of the hypertension pandemic is critical to developing public policy to reduce population level sodium exposure and blood pressure. We draw from a robust field of evidence to show that reducing sodium intake improves blood pressure in a linear fashion, across the lifespan, at an individual level and a population level, and may even reduce CVD events. While potassium plays an important role in blood pressure regulation, potassium interventions are less effective at reducing blood pressure, carry risk of hyperkalemia in select populations, and are more logistically challenging. There is an urgent need for nation-wide policies to reduce sodium intake to help stem the hypertension pandemic and prevent CVD.
心血管疾病(CVD)的全球负担持续增加,高血压的发病率也是如此,高血压是 CVD 最重要的可改变危险因素之一。需要采取非药物的、针对人群的干预措施来阻止高血压的流行,但对于公共政策的重点应该更多地放在减少饮食中的钠摄入还是增加钾摄入,目前仍存在争议。在这篇评论中,我们总结了支持减少钠摄入的政策的论点。认识到饮食中钠的增加是导致高血压流行的原因之一,对于制定减少人群中钠暴露和血压的公共政策至关重要。我们从大量证据中得出结论,表明减少钠的摄入以线性方式改善血压,跨越整个生命周期,在个体水平和人群水平上,甚至可能降低 CVD 事件的发生。虽然钾在血压调节中起着重要作用,但钾干预措施降低血压的效果较差,在某些人群中存在高钾血症的风险,并且在操作上更具挑战性。迫切需要全国性的政策来减少钠的摄入,以帮助阻止高血压的流行并预防 CVD。