Lopes Raquel Marianna, Turbino Miriam Lacalle, Zezell Denise Maria, Scaramucci Tais, Aranha Ana Cecilia Corrêa
Am J Dent. 2015 Oct;28(5):297-302.
To evaluate the effect of desensitizing dentifrices on dentin erosive wear, using a 5-day erosion-abrasion-remineralization cycling model. The effect of the dentifrices on dentin's tubule occlusion was also investigated.
30 samples of root dentin were randomly divided into three groups (n = 10): (1) Colgate Total 12 Clean Mint (control, 1,450 ppm F); (2) Colgate Sensitive Pro-Relief (1,450 ppm F, Pro-Argin); and (3) Sensodyne Repair&Protect (1,450 ppm F, Novamin). Erosion was performed with a cola drink, for 5 minutes, 4x/day. Toothbrushing with the slurry dentifrices (1:2) was performed 2x/day, with electric toothbrushes, using standard pressure for 15 seconds. Surface loss (SL) was determined with optical profilometry at baseline and after the first, third and fifth days of cycling. Before treatment and in the end of the cycling, the amount of opened dentin tubules per area was evaluated in three randomly selected specimens from each group, by environmental scanning electron microscopy. The relative dentin abrasitivity (RDA) of the dentifrices was also measured. Data were statistically analyzed (α = 0.05).
All the dentifrices showed a progressive increase in SL over time. However, no significant differences in SL among the dentifrices were observed at any time studied. Sensodyne Repair&Protect significantly reduced the number of opened dentin tubules when compared to the other groups. Colgate Total 12 Clean Mint showed the highest RDA, followed by Sensodyne Repair&Protect and then by Colgate Sensitive Pro-Relief. The desensitizing dentifrices tested produced a similar rate of erosive dentin wear to the conventional dentifrice; however, only Sensodyne Repair&Protect was able to promote tubule occlusion.
使用为期5天的侵蚀-磨损-再矿化循环模型,评估脱敏牙膏对牙本质侵蚀性磨损的影响。同时研究牙膏对牙本质小管封闭的作用。
30个牙根牙本质样本随机分为三组(n = 10):(1)高露洁全效清新薄荷牙膏(对照组,含氟1450 ppm);(2)高露洁敏感专业修复牙膏(含氟1450 ppm,含精氨酸);(3)舒适达修复护理牙膏(含氟1450 ppm,含诺华敏)。用可乐饮料进行侵蚀,每次5分钟,每天4次。使用电动牙刷,以标准压力每天2次用牙膏糊剂(1:2)刷牙15秒。在基线以及循环的第一天、第三天和第五天后,用光学轮廓仪测定表面损失(SL)。在治疗前和循环结束时,通过环境扫描电子显微镜对每组随机选取的三个样本中每单位面积开放的牙本质小管数量进行评估。还测量了牙膏的相对牙本质磨损性(RDA)。对数据进行统计学分析(α = 0.05)。
所有牙膏的SL均随时间逐渐增加。然而,在任何研究时间点,各牙膏之间的SL均未观察到显著差异。与其他组相比,舒适达修复护理牙膏显著减少了开放的牙本质小管数量。高露洁全效清新薄荷牙膏的RDA最高,其次是舒适达修复护理牙膏,然后是高露洁敏感专业修复牙膏。所测试的脱敏牙膏产生的侵蚀性牙本质磨损速率与传统牙膏相似;然而,只有舒适达修复护理牙膏能够促进小管封闭。