Modabbernia Amirhossein, Yaghoubidoust Mohammadhossein, Lin Chung-Ying, Fridlund Bengt, Michalak Erin E, Murray Greg, Pakpour Amir H
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Social Determinants of Health Research Center, Qazvin University of Medical Sciences, Shahid Bahounar BLV, Qazvin, 3419759811, Iran.
Qual Life Res. 2016 Jul;25(7):1835-44. doi: 10.1007/s11136-015-1223-0. Epub 2015 Dec 29.
To assess the reliability, validity, and factor structure of the Persian Brief Quality of Life in Bipolar Disorder (QoL.BD) in Iranian patients with bipolar disorder (BD).
After translation and cross-cultural adaptation of the Brief QoL.BD, we administered the questionnaire to 184 patients diagnosed with BD. To determine factor structure, we performed both exploratory and confirmatory factor analyses. To investigate the reliability, we assessed internal consistency, reproducibility and agreement. Construct validity was assessed by calculating correlations between the Brief QoL.BD and the Short Form-36 (SF-36), Positive And Negative Affect Schedule (PANAS), Hamilton Depression Rating Scale, Young Mania Rating Scale (YMRS) and Quality of Life Enjoyment and Satisfaction Questionnaire Short Form (Q-LES-Q-SF). We also investigated gender differences in interpretations of QoL.BD items.
The results obtained from reliability analysis confirmed internal consistency (Cronbach's alpha was 0.87 and 0.89 for two assessments) and reproducibility and agreement (the intraclass correlation coefficient ranged between 0.74 and 0.94). Validity analyses showed that the items loaded on a single-factor structure. The inter-item correlations varied from 0.31 to 0.68. Significantly lower scores on the Brief QoL.BD were observed in people diagnosed with BD I compared to BD II. Significant correlations were observed between the Brief QoL.BD and SF-36 summary measures, HAMD, YMRS, Q-LES-Q-SF and PANAS subscales. Items in the Brief QoL.BD were interpreted similarly by men and women.
The Brief Persian QoL.BD is a psychometrically sound measure with acceptable validity and reliability and provides a rapid assessment tool for measuring QoL in patients with BD.
评估波斯文版双相情感障碍简易生活质量量表（QoL.BD）在伊朗双相情感障碍（BD）患者中的信度、效度和因子结构。
对简易QoL.BD进行翻译和跨文化调适后，我们将该问卷施用于184例确诊为BD的患者。为确定因子结构，我们进行了探索性和验证性因子分析。为研究信度，我们评估了内部一致性、可重复性和一致性。通过计算简易QoL.BD与简明健康调查量表（SF-36）、正负性情绪量表（PANAS）、汉密尔顿抑郁量表、杨氏躁狂量表（YMRS）以及生活质量享受与满意度问卷简表（Q-LES-Q-SF）之间的相关性来评估结构效度。我们还研究了QoL.BD项目解读中的性别差异。
信度分析结果证实了内部一致性（两次评估的克朗巴哈系数分别为0.87和0.89）以及可重复性和一致性（组内相关系数在0.74至0.94之间）。效度分析表明，各项目加载于单因子结构上。项目间相关性在0.31至0.68之间。与双相II型障碍患者相比，双相I型障碍患者的简易QoL.BD得分显著更低。在简易QoL.BD与SF-36汇总指标、汉密尔顿抑郁量表、杨氏躁狂量表、Q-LES-Q-SF和PANAS分量表之间观察到显著相关性。男性和女性对简易QoL.BD项目的解读相似。
波斯文版简易QoL.BD是一种心理测量学上合理的测量工具，具有可接受的效度和信度，为测量双相情感障碍患者的生活质量提供了一种快速评估工具。
