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杯[n]芳烃包覆银纳米颗粒的生物应用

Bio-Applications of Calix[n]arene Capped Silver Nanoparticles.

作者信息

Tauran Yannick, Kim Beomjoon, Coleman Anthony W

出版信息

J Nanosci Nanotechnol. 2015 Sep;15(9):6308-26. doi: 10.1166/jnn.2015.10850.

Abstract

During the 10 last years, there has been a growing interest in calix[n]arene capped silver nanoparticles for their uses in biosensing and much more recently for their intrinsic therapeutic properties. Cost effective, portable and ultra-sensitive analytical tools are one of the major expectations of silver nanoparticles capped with calix[n]arenes. Their uses for detecting a wide range of hazardous molecules and biological compounds by different physical approaches (optical or electrical) are reviewed in depth here. A second part deals with their biological activities. These hybrid nanoparticles have been shown to possess antibacterial properties, and to reach antiviral and anti-cancer targets.

摘要

在过去十年中,杯[n]芳烃包覆的银纳米颗粒因其在生物传感中的应用以及最近发现的内在治疗特性而受到越来越多的关注。具有成本效益、便携且超灵敏的分析工具是杯[n]芳烃包覆银纳米颗粒的主要期望之一。本文深入综述了它们通过不同物理方法(光学或电学)检测多种有害分子和生物化合物的用途。第二部分讨论了它们的生物活性。这些杂化纳米颗粒已被证明具有抗菌特性,并能作用于抗病毒和抗癌靶点。

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