Qualls Hannah E, Mitchell Ryan M, Deubner Heike, Moe Kris S, Sardesai Maya
Department of Otolaryngology, Head and Neck Surgery, University of Minnesota Medical School, Minneapolis, Minnesota.
Department of Otolaryngology - Head and Neck Surgery, University of Washington, Seattle, Washington.
Head Neck. 2016 May;38(5):E99-104. doi: 10.1002/hed.24330. Epub 2015 Dec 30.
Laryngeal angiosarcoma is rare and the prognosis is poor. The purpose of this study was to describe the first case of cutaneous angiosarcoma metastatic to the larynx and systematically review all cases of laryngeal angiosarcoma.
A 61-year-old man presented with an alar lesion diagnosed as angiosarcoma and was treated with wide local resection and radiation. Six years later, he presented with a laryngeal mass histologically similar to the initial tumor. A systematic review of reported cases of angiosarcoma of the larynx was performed.
Eighteen cases were identified. Mean age of presentation was 64.3 years. Men represented 66.7%. Mean follow-up was 34.1 months. Forty-seven percent died with disseminated disease at a mean of 18.4 months. Our patient did well with serial resection.
To the best of our knowledge, this case represents the first documented case of cutaneous angiosarcoma metastatic to the larynx and suggests that serial resection with long-term surveillance may be of benefit in some cases.
喉血管肉瘤罕见，预后较差。本研究的目的是描述首例皮肤血管肉瘤转移至喉部的病例，并对所有喉血管肉瘤病例进行系统回顾。
一名61岁男性患者，鼻翼部病损诊断为血管肉瘤，接受了广泛局部切除及放疗。6年后，他出现喉部肿物，组织学检查与初始肿瘤相似。对已报道的喉血管肉瘤病例进行了系统回顾。
共识别出18例病例。发病的平均年龄为64.3岁。男性占66.7%。平均随访时间为34.1个月。47%的患者死于播散性疾病，平均病程为18.4个月。我们的患者经系列切除后情况良好。
据我们所知，该病例是首例有记录的皮肤血管肉瘤转移至喉部的病例，提示在某些情况下，系列切除及长期监测可能有益。
