Lebwohl Mark G, Kavanaugh Arthur, Armstrong April W, Van Voorhees Abby S
The Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, 5th Floor, 5 East 98th Street, Box 1048, New York, NY, 10029, USA.
School of Medicine, University of California, San Diego, La Jolla, CA, USA.
Am J Clin Dermatol. 2016 Feb;17(1):87-97. doi: 10.1007/s40257-015-0169-x.
The Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP), a population-based survey of patients, dermatologists, and rheumatologists, was conducted for better understanding of the unmet needs of psoriasis and psoriatic arthritis (PsA) patients.
To report results from US physicians and patients.
Adults were contacted by household telephone, using random digit dialing, and asked to participate if they had ever been diagnosed with psoriasis or PsA. Physicians were identified through national databases and contacted through random sampling methods.
In the USA, 1005 patients, 101 dermatologists, and 100 rheumatologists were surveyed. PsA had been diagnosed in 270 patients (26.9%). Of those with psoriasis alone, fewer than 60% (versus 85.6% of PsA patients) had seen a healthcare provider within 12 months. Joint pain was reported by 51.8% of psoriasis patients without a diagnosis of PsA, and 37.6% of dermatologists cited their greatest challenge in managing PsA patients as being differentiating PsA from other arthritic diseases. Itching was reported by 36% of psoriasis patients versus 12% of dermatologists as the most important factor contributing to disease severity. Patients reported lower rates of current treatment than did dermatologists and rheumatologists. Conventional oral and biologic therapies were used by 24.9 and 17.7% of patients, respectively. Among patients who had received injectable biologics, treatment dissatisfaction was related to long-term safety/tolerability, injection-related anxiety/fear, and cost.
This large, population-based survey identified unmet needs in the management of psoriasis and PsA patients in the USA, including assessment of disease severity, PsA diagnosis, undertreatment, and satisfaction with therapy.
银屑病和银屑病关节炎多国评估(MAPP)是一项针对患者、皮肤科医生和风湿病学家的基于人群的调查,旨在更好地了解银屑病和银屑病关节炎(PsA)患者未满足的需求。
报告美国医生和患者的调查结果。
通过随机数字拨号进行家庭电话联系成年人群体,询问他们是否曾被诊断患有银屑病或PsA,若符合则邀请参与调查。医生通过国家数据库识别,并通过随机抽样方法进行联系。
在美国,共调查了1005名患者、101名皮肤科医生和100名风湿病学家。270名患者(26.9%)被诊断患有PsA。仅患有银屑病的患者中,不到60%(相比PsA患者的85.6%)在12个月内看过医疗服务提供者。未诊断为PsA的银屑病患者中有51.8%报告有关节疼痛,37.6%的皮肤科医生表示,他们在管理PsA患者时面临的最大挑战是将PsA与其他关节炎疾病区分开来。36%的银屑病患者报告瘙痒是导致疾病严重程度的最重要因素,而皮肤科医生中这一比例为12%。患者报告的当前治疗率低于皮肤科医生和风湿病学家。分别有24.9%和17.7%的患者使用传统口服和生物疗法。在接受注射用生物制剂治疗的患者中,治疗不满意与长期安全性/耐受性、注射相关焦虑/恐惧和成本有关。
这项基于人群的大型调查确定了美国银屑病和PsA患者管理中未满足的需求,包括疾病严重程度评估、PsA诊断、治疗不足以及对治疗的满意度。