Duan Dongsheng, Rafael-Fortney Jill A, Blain Alison, Kass David A, McNally Elizabeth M, Metzger Joseph M, Spurney Christopher F, Kinnett Kathi
Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA.
Department of Neurology, School of Medicine, University of Missouri, Columbia, MO, USA.
J Cardiovasc Transl Res. 2016 Feb;9(1):85-6. doi: 10.1007/s12265-015-9669-6. Epub 2015 Dec 30.
A recent working group meeting focused on contemporary cardiac issues in Duchenne muscular dystrophy (DMD) was hosted by the National Heart, Lung, and Blood Institute in collaboration with the Parent Project Muscular Dystrophy. An outcome of this meeting was to provide freely available detailed protocols for preclinical animal studies. The goal of these protocols is to improve the quality and reproducibility of cardiac preclinical studies aimed at developing new therapeutics for the prevention and treatment of DMD cardiomyopathy.
美国国立心肺血液研究所与肌肉萎缩症家长项目合作主办了一次近期的工作组会议,会议聚焦于杜氏肌营养不良症(DMD)的当代心脏问题。本次会议的一个成果是提供了用于临床前动物研究的免费详细方案。这些方案的目标是提高旨在开发预防和治疗DMD心肌病新疗法的心脏临床前研究的质量和可重复性。