Cote G, Jequier S, Kaplan P
Department of Radiology, Montreal Children's Hospital, McGill University, Quebec, Canada.
Pediatr Radiol. 1989;19(6-7):481-3. doi: 10.1007/BF02387666.
Williams syndrome is characterized by peripheral artery stenosis such as supravalvular aortic stenosis, a distinctive dysmorphic facies, mental retardation and occasionally by transient infantile hypercalcemia. Twenty-five children with this syndrome underwent abdominal ultrasound examinations in our institution between 1983-1988. Five showed an increase in the renal medullary echogenicity consistent with medullary nephrocalcinosis. The echogenicity did not change with time. Two of the five had documented hypercalcemia in infancy. The other three did not have calcium measurements in infancy. No patient with normal serum calcium measurements during infancy developed nephrocalcinosis. Renal ultrasound may add information as to the incidence of infantile hypercalcemia in Williams syndrome.
威廉姆斯综合征的特征是外周动脉狭窄，如瓣上主动脉狭窄、独特的畸形面容、智力迟钝，偶尔还会出现短暂的婴儿高钙血症。1983年至1988年期间，25名患有该综合征的儿童在我们机构接受了腹部超声检查。5名儿童显示肾髓质回声增强，符合髓质肾钙质沉着症。回声随时间没有变化。这5名儿童中有2名在婴儿期有高钙血症记录。另外3名儿童在婴儿期未进行钙测量。婴儿期血清钙测量正常的患者均未发生肾钙质沉着症。肾脏超声检查可能会提供有关威廉姆斯综合征婴儿高钙血症发病率的信息。
