Raffoux C, Rabian C, Gluckman E
GMFT, Laboratoire d'Immunologie et d'Histocompatibilité, Hôpital Saint-Louis, Paris, France.
Nouv Rev Fr Hematol (1978). 1989;31(2):167-9.
A program to obtain volunteer bone marrow donors has been developed. A total of 33.000 HLA-A, B typings were performed. A search for 527 patients has been initiated. Among these, 44% are suffering from chronic myelogenous leukemia. For 23% of the patients no HLA-A, B identical donor has been identified. Out of the 401 patients who had HLA-A, B identical donor 35% (139/401) had one or more HLA-A, B, DR identical donors. In one of the transplant center, when the mixed lymphocyte culture (MLR) was carried out between 219 donors and 79 patients, a transplantation for 20/79 patients has been proposed. Up to now, transplantation has been carried out in 31 patients whom donor searches were initiated.
一个获取志愿骨髓捐赠者的项目已经开展。总共进行了33000次HLA - A、B分型。已经开始为527名患者寻找捐赠者。其中，44%患有慢性粒细胞白血病。23%的患者尚未找到HLA - A、B配型相同的捐赠者。在401名有HLA - A、B配型相同捐赠者的患者中，35%（139/401）有一个或多个HLA - A、B、DR配型相同的捐赠者。在其中一个移植中心，当对219名捐赠者和79名患者进行混合淋巴细胞培养（MLR）时，已提议为20/79的患者进行移植。到目前为止，在已开始寻找捐赠者的31名患者中已经进行了移植。
