Tanaka H, Akaza T, Juji T
Japanese Red Cross Central Blood Center, Tokyo, Japan.
Clin Transpl. 1996:139-44.
The Japan Marrow Donor Program started to recruit donors at the beginning of 1992 with the financial support of the Japanese government, and the first unrelated bone marrow transplantation arranged through this program was performed in 1993. Since 1992, about 82,000 donors and 4,400 patients have been registered. At least one HLA-identical donor has been found for 60% of the patients in the first search after the patients register with the JMDP, and as of the end of September 1996, 880 patients had received bone marrow transplants from unrelated donors. The results of 19.7% of registered patients having received bone marrow transplants and 1.1% of registered donors having donated far exceed our forecasts. This is attributed to the high frequency of several haplotypes in the Japanese. However, no HLA-identical donors have been found for approximately 800 registered patients so far. Thus, it is still necessary to increase the number of donors registered with the JMDP.
日本骨髓捐赠项目于1992年初在日本政府的财政支持下开始招募捐赠者，通过该项目安排的首例非亲属骨髓移植于1993年进行。自1992年以来，约有82000名捐赠者和4400名患者进行了登记。在患者向日本骨髓捐赠项目登记后的首次搜索中，60%的患者至少找到了一名HLA匹配的捐赠者，截至1996年9月底，880名患者接受了非亲属捐赠者的骨髓移植。19.7%的登记患者接受了骨髓移植，1.1%的登记捐赠者进行了捐赠，这一结果远远超出了我们的预期。这归因于日本人中几种单倍型的高频率。然而，到目前为止，约800名登记患者尚未找到HLA匹配的捐赠者。因此，仍有必要增加在日本骨髓捐赠项目登记的捐赠者数量。
