Liu Donglei, Yang Yang, Qi Y U, Wu Kai, Zhao Song
Department of Thoracic Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Oncol Lett. 2015 Nov;10(5):3161-3162. doi: 10.3892/ol.2015.3659. Epub 2015 Sep 2.
Esophageal schwannoma is a rare tumor among the thoracic diseases. The current study reports the case of a 62-year-old who presented with a 1-month history of dysphasia. A computed tomography scan of the chest revealed a solid mediastinal mass with a maximum diameter of 8 cm, with inhomogeneous enhancement following injection of contrast. The mass was compressing the trachea and esophagus. Subsequent to cisplatin plus fluorouracil infusion and embolization with a gelatin sponge, a standard right-sided posterolateral surgical procedure was performed in the right thorax, with tumor enucleation and mucosal repair. The diagnosis of esophageal schwannoma was confirmed by pathological examination. Microscopic examination revealed spindle cells, with the positive expression of S-100 protein and negative expression results for endothelial membrane antigen and desmin, confirming the diagnosis of esophageal schwannoma.
食管神经鞘瘤是胸部疾病中一种罕见的肿瘤。本研究报告了一例62岁患者,有1个月吞咽困难病史。胸部计算机断层扫描显示纵隔有一实性肿块,最大直径为8cm,注入造影剂后强化不均匀。该肿块压迫气管和食管。在顺铂加氟尿嘧啶输注及明胶海绵栓塞后,在右胸进行了标准的右侧后外侧手术,完整摘除肿瘤并修复黏膜。病理检查确诊为食管神经鞘瘤。显微镜检查显示梭形细胞,S-100蛋白呈阳性表达,内皮细胞膜抗原和结蛋白呈阴性表达结果,确诊为食管神经鞘瘤。