Ferrante Marc, Khan Arfa, Fan Cathy, Jelloul Fatima Zahra
North Shore-Long Island Jewish Health System , New Hyde Park, NY, USA.
Rare Tumors. 2014 Jun 25;6(2):5361. doi: 10.4081/rt.2014.5361. eCollection 2014 May 13.
Esophageal schwannoma is a rare tumor first described in 1967 by Chaterlin and Fissore. These tumors are most commonly found incidentally or from diagnostic work up of dysphagia or dyspnea. This entity cannot be diagnosed on clinical or radiographic basis alone. Histology demonstrates palisading spindle cells, few if any mitotic figures, and a peripheral cuff of lymphoid cells. Immunohistochemically, tumor cells stain positive for S100, a characteristic marker of Schwann cells. Once diagnosed, surgical enucleation is the typical treatment method employed.
食管神经鞘瘤是一种罕见肿瘤,1967年由沙泰兰和菲索雷首次描述。这些肿瘤最常偶然发现,或在吞咽困难或呼吸困难的诊断检查中发现。仅凭临床或影像学检查无法诊断该疾病。组织学表现为栅栏状梭形细胞,极少有丝分裂象,以及淋巴细胞外周套。免疫组化方面,肿瘤细胞S100染色呈阳性,这是施万细胞的特征性标志物。一旦确诊,手术摘除是常用的典型治疗方法。