Division of Cardiovascular Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pa.
Department of Anesthesia, University of Pennsylvania School of Medicine, Philadelphia, Pa.
J Thorac Cardiovasc Surg. 2016 Apr;151(4):1073-8. doi: 10.1016/j.jtcvs.2015.11.027. Epub 2015 Nov 25.
We describe an alternate technique for establishing antegrade cerebral perfusion (ACP) during hypothermic circulatory arrest via direct, central cannulation of the innominate artery.
From 2009 to 2015, 100 elective hemiarch reconstructions for proximal aortic aneurysms were performed under moderate hypothermic circulatory arrest (MHCA). Cerebral perfusion was instituted with ACP via direct cannulation of the innominate artery.
Mean patient age was 63 ± 13 years (72 men; 72%). Mean MHCA temperature was 27.3°C ± 1.0°C (median, 28°C). Mean ACP time was 17 ± 4 minutes and mean crossclamp time was 134 ± 42 minutes. Proximal reconstruction included root replacement with composite valved graft (n = 47), valve sparing root reimplantation (n = 16), and aortic valve replacement (n = 19). In-hospital 30-day mortality (n = 1; 1%), stroke (1; 1%), reversible ischemic neurologic deficit (n = 1; 1%), coma (n = 0), and renal failure (n = 1; 1%) rates were low. There was no incidence of injury or dissection of the innominate artery.
Direct, central innominate artery cannulation for ACP yields excellent outcomes. This technique is safe, provides excellent cerebral protection during circulatory arrest and simplifies the circulatory management strategy for elective ascending aortic and hemiarch reconstruction.
我们描述了一种通过直接对无名动脉进行中央插管来建立低温循环停止期间顺行大脑灌注(ACP)的替代技术。
2009 年至 2015 年,100 例近端主动脉瘤的选择性半弓重建在中度低温循环停止(MHCA)下进行。通过直接插管无名动脉来建立 ACP 以进行脑灌注。
患者平均年龄为 63 ± 13 岁(72 名男性;72%)。平均 MHCA 温度为 27.3°C ± 1.0°C(中位数,28°C)。平均 ACP 时间为 17 ± 4 分钟,平均夹闭时间为 134 ± 42 分钟。近端重建包括带复合瓣的根部置换(n = 47)、保留瓣膜根部再植入(n = 16)和主动脉瓣置换(n = 19)。院内 30 天死亡率(n = 1;1%)、中风(1;1%)、可逆性缺血性神经功能缺损(n = 1;1%)、昏迷(n = 0)和肾衰竭(n = 1;1%)发生率较低。无名动脉没有损伤或夹层的发生。
直接对无名动脉中央插管进行 ACP 可获得良好的结果。该技术安全,在循环停止期间提供出色的脑保护,并简化了选择性升主动脉和半弓重建的循环管理策略。