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温性主动脉弓修复:一种新方法。

Warm aortic arch repair: A new approach.

作者信息

Fukuhara Shinichi, Hawkins Robert B, Ailawadi Gorav, Hamilton Barbara

机构信息

Department of Cardiac Surgery, University of Michigan, Ann Arbor, Mich.

出版信息

JTCVS Tech. 2025 Jan 23;31:18-31. doi: 10.1016/j.xjtc.2025.01.003. eCollection 2025 Jun.

Abstract

OBJECTIVES

We present a streamlined approach for aortic arch repair that does not require hypothermic circulatory arrest or axillary/femoral cutdown.

METHODS

The procedure setup comprised standard right radial/femoral arterial lines, near-infrared spectroscopy, sternotomy, and cardiopulmonary bypass with arch central cannulation. Under normothermia, antegrade cerebral perfusion (ACP) was administered through the innominate artery via punctured aortic root needle cannula (closed ACP) or balloon catheter (open ACP). Aortic arch clamping followed, with bilateral ACP employed in selected cases. From 2019 to 2024, a total of 153 patients, including 48 (30.4%) with Type A aortic dissection, underwent warm arch repair.

RESULTS

The majority of repairs involved hemiarch (n = 137 [89.5%]), with a smaller subset of patients with zone 1 (n = 5 [3.3%]) and zone 2 (n = 11 [7.2%]) arch repair. The volume of warm arch repair cases increased during the study period, with its establishment as the standard approach since 2023, regardless of aortic pathologies. Median ACP flow rates were 8.6 mL/kg/minute and 11.3 mL/kg/minute for unilateral and bilateral ACP, respectively, with a technical success rate of 99.4%. In-hospital mortality and disabling stroke were 2.0% and 1.3%, respectively. Since the launch of this approach and initial experience, 4 surgeons at our institution have adopted this technique and the clinical indications for this approach have evolved.

CONCLUSIONS

Warm aortic arch repair without hypothermic circulatory arrest or axillary/femoral cutdown is demonstrated to be safe, feasible, and reproducible. It has emerged as a new and valid approach for various aortic pathologies requiring hemiarch and selected partial aortic arch repair.

摘要

目的

我们提出一种简化的主动脉弓修复方法,该方法无需低温循环骤停或腋动脉/股动脉切开。

方法

手术设置包括标准的右桡动脉/股动脉置管、近红外光谱监测、胸骨切开术以及采用主动脉弓中央插管的体外循环。在常温下,通过无名动脉经穿刺主动脉根针导管(闭合性顺行脑灌注)或球囊导管(开放性顺行脑灌注)进行顺行脑灌注(ACP)。随后进行主动脉弓阻断,部分病例采用双侧ACP。2019年至2024年,共有153例患者接受了常温主动脉弓修复,其中48例(30.4%)为A型主动脉夹层。

结果

大多数修复涉及半弓修复(n = 137 [89.5%]),一小部分患者进行了1区(n = 5 [3.3%])和2区(n = 11 [7.2%])的主动脉弓修复。在研究期间,常温主动脉弓修复病例数量增加,自2023年起已成为标准方法,无论主动脉病变情况如何。单侧和双侧ACP的中位流量分别为8.6 mL/(kg·分钟)和11.3 mL/(kg·分钟),技术成功率为99.4%。住院死亡率和致残性卒中发生率分别为2.0%和1.3%。自该方法推出并积累初步经验以来,我们机构的4名外科医生采用了该技术,且该方法的临床适应证也有所发展。

结论

无需低温循环骤停或腋动脉/股动脉切开的常温主动脉弓修复被证明是安全、可行且可重复的。它已成为一种针对各种需要半弓及部分选择性主动脉弓修复的主动脉病变的新的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6b6/12237780/7ec4f82ccfa5/fx1.jpg

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