Hsu Nai-Wei, Tsao Hsuan-Ming, Chen Hsi-Chung, Lo Su-Shun, Chen Shih-Ann, Chou Pesus
Division of Cardiology, Department of Internal Medicine, National Yang-Ming University Hospital.
Tohoku J Exp Med. 2016 Jan;238(1):75-83. doi: 10.1620/tjem.238.75.
Atrial fibrillation (AF) is currently recognized as one of the most common cardiac arrhythmias worldwide, with the increasing prevalence that has been estimated to be as high as 9% among the elderly. Health-related quality of life (HRQoL) has become an important patient-centered health outcome measurement, but the impacts created by AF and other arrhythmias with similar symptoms, such as frequent atrial and ventricular premature contractions (APCs and VPCs, defined as ≥ 3 beats/5 minutes), have not been extensively evaluated. The Yilan Study is a population-based community health survey, which in part aims to evaluate the prevalence and impacts of these arrhythmias on the HRQoL in a community dwelling elderly population. A total of 1,732 citizens from the Yilan, Taiwan, aged 65 years or older (45.8% male) were enrolled and visited at their homes, where HRQoL was measured utilizing the Short Form-12 Health Survey. Each participant's heart rhythm was recorded with an electrocardiographic monitor for 5 minutes. The results disclosed that the prevalence of AF of this aged population was 5.8%, similar to the mean global prevalence. Besides, the prevalence of frequent APCs and frequent VPCs in these elderly people were 7.1% and 5.5%, respectively. After multiple regression analysis, elderly people with AF had lower scores in the physical component of HRQoL, while those elderly people with frequent VPCs had lower scores in the mental component. Ultimately, these findings can provide additional useful and population-specific information about AF, and assist medical professionals in designing more effective strategies for cardiac arrhythmia treatments.
心房颤动(AF)目前被认为是全球最常见的心律失常之一,其患病率不断上升,据估计在老年人中高达9%。与健康相关的生活质量(HRQoL)已成为以患者为中心的重要健康结局衡量指标,但AF以及其他具有相似症状的心律失常,如频繁房性和室性早搏(房性早搏和室性早搏,定义为≥3次/5分钟)所产生的影响尚未得到广泛评估。宜兰研究是一项基于人群的社区健康调查,部分目的是评估这些心律失常在社区老年人群中的患病率及其对HRQoL的影响。共有1732名来自中国台湾宜兰、年龄在65岁及以上的公民(男性占45.8%)被纳入研究,并在家中接受访问,使用简短健康调查问卷12项版(Short Form-12 Health Survey)对HRQoL进行测量。使用心电图监测仪记录每位参与者5分钟的心律。结果显示,该老年人群中AF的患病率为5.8%,与全球平均患病率相似。此外,这些老年人中频繁房性早搏和频繁室性早搏的患病率分别为7.1%和5.5%。经过多元回归分析,患有AF的老年人在HRQoL的身体维度得分较低,而患有频繁室性早搏的老年人在心理维度得分较低。最终,这些发现可以提供有关AF的更多有用且针对特定人群的信息,并协助医疗专业人员设计更有效的心律失常治疗策略。