通过内镜超声引导下细针穿刺活检结果诊断的原发性胰腺恶性淋巴瘤

Primary Pancreatic Malignant Lymphoma Diagnosed from Endoscopic Ultrasound-guided Fine-needle Aspiration Findings.

作者信息

Fukuba Nobuhiko, Moriyama Ichiro, Ishihara Shunji, Sonoyama Hiroki, Yamashita Noritsugu, Tada Yasumasa, Oka Akihiko, Oshima Naoki, Yuki Takafumi, Kawashima Kousaku, Kinoshita Yoshikazu

机构信息

Department of Internal Medicine II, Shimane University School of Medicine, Japan.

出版信息

Intern Med. 2016;55(1):31-5. doi: 10.2169/internalmedicine.55.5749. Epub 2016 Jan 1.

DOI:10.2169/internalmedicine.55.5749

PMID:26726082

Abstract

A 60-year-old woman was admitted to our hospital with upper abdominal pain and jaundice. Computed tomography showed a 9-cm mass that was penetrated by the common hepatic artery in the pancreatic head area. Endoscopic retrograde pancreatography revealed no stenosis or obstruction of the main pancreatic duct, and a cytologic examination of the patient's pancreatic juice was negative. Next, endoscopic ultrasound-guided fine needle aspiration was performed. The immunohistological findings of the specimen revealed a diffuse large B-cell lymphoma. The size of the tumor was significantly reduced after 8 cycles of R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone).

摘要

一名60岁女性因上腹部疼痛和黄疸入住我院。计算机断层扫描显示胰头区域有一个9厘米的肿块，肝总动脉穿过该肿块。内镜逆行胰胆管造影显示主胰管无狭窄或阻塞，患者胰液的细胞学检查为阴性。接下来，进行了内镜超声引导下细针穿刺抽吸。标本的免疫组织学检查结果显示为弥漫性大B细胞淋巴瘤。接受8个周期的R-CHOP化疗（利妥昔单抗、环磷酰胺、多柔比星、长春新碱和泼尼松龙）后，肿瘤大小显著缩小。