Breitenbach M, Achatz G, Heger S, Hufnagl P, Wallner J, Eichler M, Spevak W, Schweiger C, Rumpold H
Institut für Mikrobiologie und Genetik, Universität Wien.
Wien Klin Wochenschr. 1989 Aug 4;101(15):495-504.
This short review article discusses methods and results of oncogene research in yeast. Current knowledge of the sequence, expression and biological function of ras-homologous genes of the yeast Saccharomyces cerevisiae is presented, as well as the implications of these findings for oncogene research in mammals. We review recent examples of highly conserved eukaryotic genes involved in growth control and mitosis control, including recent work from our own laboratories.
这篇简短的综述文章讨论了酵母中癌基因研究的方法和结果。介绍了酿酒酵母中ras同源基因的序列、表达和生物学功能的当前知识，以及这些发现对哺乳动物癌基因研究的意义。我们综述了涉及生长控制和有丝分裂控制的高度保守的真核基因的近期实例，包括我们自己实验室的近期工作。
