Waldecker B, Frees U, Brachmann J, Thorspecken R, Kübler W
Medizinische Klinik III der Universität, Heidelberg.
Z Kardiol. 1989 Jul;78(7):453-8.
131 patients received permanent pacemakers to treat their hypersensitive carotis sinus syndrome (HCSS). Prior to implantation, HCSS was diagnosed whenever spontaneous episodes of faintness or dizziness (n = 25) or syncope (n = 106) coincided with an abnormal response to carotis sinus massage (asystole greater than 3 s). 123 patients were followed for 48 +/- 27 months after implantation to assess the value of pacemaker therapy. 77% of all patients were free of initial symptoms. 90% of patients with syncope prior to pacemaker therapy were free of recurrence. Therefore, permanent pacing appears to be the treatment of choice for these patients. Since carotis sinus massage produced high-degree AV-block in at least 33% of patients, ventricular (rather than exclusive atrial) pacing seems to be mandatory. However, syncope did recur in 10% despite normal pacemaker function. The etiology of these recurrences remained unclear in almost all patients. As opposed to patients with syncope, cardiac pacing prevented symptoms in only 26% of patients with faintness or dizziness without full syncope. In these patients primary and sole pacemaker therapy does not appear to be appropriate.
131例患者接受了永久性起搏器植入治疗其颈动脉窦综合征(HCSS)。植入前,只要晕厥或头晕的自发发作(n = 25)或晕厥(n = 106)与颈动脉窦按摩的异常反应(心脏停搏大于3秒)同时出现,即可诊断为HCSS。123例患者在植入后随访48±27个月,以评估起搏器治疗的价值。所有患者中有77%无初始症状。起搏器治疗前有晕厥的患者中,90%无复发。因此,永久性起搏似乎是这些患者的首选治疗方法。由于颈动脉窦按摩在至少33%的患者中产生高度房室传导阻滞,心室(而非单纯心房)起搏似乎是必要的。然而,尽管起搏器功能正常,仍有10%的患者复发晕厥。几乎所有患者这些复发的病因仍不清楚。与晕厥患者不同,心脏起搏仅使26%无完全晕厥的头晕或眩晕患者症状得到缓解。在这些患者中,单纯的起搏器治疗似乎并不合适。