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立体定向脊髓三叉神经核切开术治疗颅面部带状疱疹后神经痛

Craniofacial postherpetic neuralgia managed by stereotactic spinal trigeminal nucleotomy.

作者信息

Schvarcz J R

机构信息

School of Medicine, University of Buenos Aires, Argentina.

出版信息

Acta Neurochir Suppl (Wien). 1989;46:62-4. doi: 10.1007/978-3-7091-9029-6_14.

Abstract

Postherpetic craniofacial neuralgias are notoriously difficult to deal with. Nevertheless, stereotactic spinal trigeminal nucleotomy seems to be a rational approach, as both experimental and clinical data strongly suggest the relevance of nucleus caudalis for certain facial neurogenic pain phenomena. From a series of 136 consecutive nucleotomies, 80 were performed for deafferentation pain. The long-term results of 25 such cases, who underwent this procedure for postherpetic neuralgia, are reported. Their pain was referred to the Vth, to the VII, IX and Xth, and to the C2-3 dermatomes. Abolition of the allodynia, and disappearance of, or marked reduction in, the deep background pain was achieved in 76% of the cases overall. The follow-up period ranged from 1 to 13 years. There was no untoward side-effects. Technical and electrophysiological data germane to accurate target placement are discussed. Spinal trigeminal nucleotomy is then a specially suitable procedure for postherpetic craniofacial dysaesthesiae.

摘要

疱疹后颅面部神经痛 notoriously 难以处理。然而,立体定向脊髓三叉神经核切除术似乎是一种合理的方法,因为实验和临床数据都有力地表明尾状核与某些面部神经源性疼痛现象相关。在连续的136例核切除术中,80例是为了治疗去传入性疼痛而进行的。本文报告了25例因疱疹后神经痛接受该手术的此类病例的长期结果。他们的疼痛涉及第V、VII、IX和X颅神经以及C2 - 3皮节。总体而言,76%的病例实现了异常性疼痛的消除以及深部背景疼痛的消失或显著减轻。随访期为1至13年。未出现不良副作用。讨论了与精确靶点定位相关的技术和电生理数据。因此,脊髓三叉神经核切除术是治疗疱疹后颅面部感觉异常的一种特别合适的手术。

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