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在印度法里达巴德地区实施新生儿和儿童疾病综合管理项目的成本效益

Cost Effectiveness of Implementing Integrated Management of Neonatal and Childhood Illnesses Program in District Faridabad, India.

作者信息

Prinja Shankar, Bahuguna Pankaj, Mohan Pavitra, Mazumder Sarmila, Taneja Sunita, Bhandari Nita, van den Hombergh Henri, Kumar Rajesh

机构信息

School of Public Health, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

UNICEF India Country Office, New Delhi, India.

出版信息

PLoS One. 2016 Jan 4;11(1):e0145043. doi: 10.1371/journal.pone.0145043. eCollection 2016.

Abstract

INTRODUCTION

Despite the evidence for preventing childhood morbidity and mortality, financial resources are cited as a constraint for Governments to scale up the key health interventions in some countries. We evaluate the cost effectiveness of implementing IMNCI program in India from a health system and societal perspective.

METHODS

We parameterized a decision analytic model to assess incremental cost effectiveness of IMNCI program as against routine child health services for infant population at district level in India. Using a 15-years time horizon from 2007 to 2022, we populated the model using data on costs and effects as found from a cluster-randomized trial to assess effectiveness of IMNCI program in Haryana state. Effectiveness was estimated as reduction in infant illness episodes, deaths and disability adjusted life years (DALY). Incremental cost per DALY averted was used to estimate cost effectiveness of IMNCI. Future costs and effects were discounted at a rate of 3%. Probabilistic sensitivity analysis was undertaken to estimate the probability of IMNCI to be cost effective at varying willingness to pay thresholds.

RESULTS

Implementation of IMNCI results in a cumulative reduction of 57,384 illness episodes, 2369 deaths and 76,158 DALYs among infants at district level from 2007 to 2022. Overall, from a health system perspective, IMNCI program incurs an incremental cost of USD 34.5 (INR 1554) per DALY averted, USD 34.5 (INR 1554) per life year gained, USD 1110 (INR 49,963) per infant death averted. There is 90% probability for ICER to be cost effective at INR 2300 willingness to pay, which is 5.5% of India's GDP per capita. From a societal perspective, IMNCI program incurs an additional cost of USD 24.1 (INR 1082) per DALY averted, USD 773 (INR 34799) per infant death averted and USD 26.3 (INR 1183) per illness averted in during infancy.

CONCLUSION

IMNCI program in Indian context is very cost effective and should be scaled-up as a major child survival strategy.

摘要

引言

尽管有证据表明可预防儿童发病和死亡,但在一些国家,财政资源被视为政府扩大关键卫生干预措施的制约因素。我们从卫生系统和社会角度评估在印度实施综合管理儿童疾病(IMNCI)项目的成本效益。

方法

我们构建了一个决策分析模型,以评估在印度地区层面,相对于针对婴儿群体的常规儿童保健服务,IMNCI项目的增量成本效益。从2007年到2022年采用15年的时间跨度,我们使用在一项整群随机试验中发现的成本和效果数据来填充该模型,以评估IMNCI项目在哈里亚纳邦的效果。效果估计为婴儿疾病发作、死亡和伤残调整生命年(DALY)的减少。每避免一个DALY的增量成本用于估计IMNCI的成本效益。未来成本和效果按3%的贴现率进行贴现。进行概率敏感性分析以估计在不同支付意愿阈值下IMNCI具有成本效益的概率。

结果

2007年至2022年期间,在地区层面实施IMNCI使婴儿的疾病发作累计减少57384例,死亡减少2369例,DALY减少76158个。总体而言,从卫生系统角度来看,IMNCI项目每避免一个DALY的增量成本为34.5美元(1554印度卢比),每获得一个生命年的增量成本为34.5美元(1554印度卢比),每避免一例婴儿死亡的增量成本为1110美元(49963印度卢比)。在支付意愿为2300印度卢比时,成本效果比具有成本效益的概率为90%,这是印度人均国内生产总值的5.5%。从社会角度来看,IMNCI项目每避免一个DALY的额外成本为24.1美元(1082印度卢比),每避免一例婴儿死亡的额外成本为773美元(34799印度卢比),每避免一次婴儿期疾病发作的额外成本为26.3美元(1,183印度卢比)。

结论

在印度背景下,IMNCI项目具有很高的成本效益,应作为一项主要的儿童生存战略加以扩大实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8e7/4699694/23d75b55dbff/pone.0145043.g001.jpg

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