Cheng Yvonne Kwun Yue, Yu Simon Chun Ho, So Po Lam, Leung Tak Yeung
Department of Obstetrics and Gynaecology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Fetal Diagn Ther. 2017;41(1):76-79. doi: 10.1159/000442586. Epub 2016 Jan 5.
We describe a case of large chorioangioma diagnosed at 22 weeks of gestation. As the tumour progressively enlarged to 8 cm with fetal cardiomegaly and increased middle cerebral arterial peak systolic velocity, embolisation of its feeding artery by percutaneous injection of cyanoacrylate was performed under ultrasound guidance. Devascularisation was immediate and complete, and the fetal cardiomegaly and anaemic features resolved after 3 weeks. A healthy infant was born at 34 weeks of gestation following spontaneous preterm labour. Pathological examination of the placenta confirmed an infarcted chorioangioma. Literature on the various prenatal treatments of chorioangioma was reviewed and showed that embolisation using cyanoacrylate is a feasible, simple, and effective treatment for large chorioangiomas. The techniques to optimise the success of the procedure were also discussed.
我们描述了一例在妊娠22周时诊断出的巨大绒毛膜血管瘤病例。随着肿瘤逐渐增大至8厘米，伴有胎儿心脏肥大和大脑中动脉收缩期峰值流速增加，在超声引导下经皮注射氰基丙烯酸酯对其供血动脉进行了栓塞。去血管化立即且完全成功，3周后胎儿心脏肥大和贫血特征消失。在妊娠34周时，经自然早产产下一名健康婴儿。胎盘的病理检查证实为梗死性绒毛膜血管瘤。对绒毛膜血管瘤各种产前治疗的文献进行了综述，结果表明使用氰基丙烯酸酯进行栓塞是治疗巨大绒毛膜血管瘤的一种可行、简单且有效的方法。还讨论了优化该手术成功率的技术。
