Wu T, Sun R, Huang Y, Wang Z, Yin X, Zhu Z, Zhao Z, He J
Department of Interventional Radiology, The First Affiliated Hospital of Henan University, Kaifeng, Henan 475001, PR, China.
Department of Gastrointestinal Medicine, The First Affiliated Hospital of Henan University, Kaifeng, Henan 475001, PR, China.
Indian J Cancer. 2015 Dec;52 Suppl 2:e107-11. doi: 10.4103/0019-509X.172505.
To improve patient comfort and reduce complications, clinical benefit of a transradial approach for transcatheter arterial chemoembolization (TACE) was evaluated in patients with hepatocellular carcinoma (HCC).
A total of 284 patients with HCC for TACE was divided into transradial approach group (n = 126) and transfemoral approach group (n = 158). These two groups of cases were retrospectively compared with regard to complications, the procedural time, X-ray exposure time, length of hospitalization, and hospital costs.
There were lower incidence rates of complications including abdominal distension (42.85% vs. 87.97%, P> 0.001), vomiting (53.17% vs. 77.22%, P < 0.001), lumbago (1.59% vs. 97.46%, P < 0.001), and dysuria (0% vs. 62.03%, P < 0.001) in the transradial group as compared with the transfemoral group. The time required for catheterization and total X-ray exposure time were less in the transradial group compared with the transfemoral group (Pall < 0.001). The hospital stay time and costs required for catheterization were less in the transradial group compared with the transfemoral group (P < 0.001 and P = 0.001, respectively). In addition, hepatic angiography and TACE were completed in 100% and 99.2% cases in transfemoral and transradial groups, respectively.
Transradial approach for TACE improves quality of life in patients with HCC by offering fewer complications and lower costs compared with transfemoral approach.
为提高患者舒适度并减少并发症，对经桡动脉途径行经导管动脉化疗栓塞术（TACE）治疗肝细胞癌（HCC）患者的临床获益进行评估。
将总共284例行TACE的HCC患者分为经桡动脉途径组（n = 126）和经股动脉途径组（n = 158）。对这两组病例在并发症、手术时间、X线暴露时间、住院时间和住院费用方面进行回顾性比较。
与经股动脉组相比，经桡动脉组并发症发生率较低，包括腹胀（42.85% 对87.97%，P > 0.001）、呕吐（53.17% 对77.22%，P < 0.001）、腰痛（1.59% 对97.46%，P < 0.001）和排尿困难（0% 对62.03%，P < 0.001）。与经股动脉组相比，经桡动脉组插管所需时间和总X线暴露时间更短（所有P < 0.001）。与经股动脉组相比，经桡动脉组住院时间和插管所需费用更低（分别为P < 0.001和P = 0.001）。此外，经股动脉组和经桡动脉组分别有100%和99.2%的病例完成了肝血管造影和TACE。
与经股动脉途径相比，经桡动脉途径行TACE可减少并发症并降低费用，从而提高HCC患者的生活质量。
