Sakhadeo Uma, Mundhe Rajesh, DeSouza Maria A, Chinoy Roshan F
Department of Pathology, Prince Aly Khan Hospital, Mumbai, Maharashtra, India.
J Cytol. 2015 Jul-Sep;32(3):201-3. doi: 10.4103/0970-9371.168904.
Pleomorphic lipoma is a relatively rare adipocytic neoplasm, occurring predominantly in elderly males in the subcutaneous tissues of the neck or shoulder. To the best of our knowledge, only five cases have been reported in which the lesion was intramuscular. We hereby report a case of a 60-year-old female patient, presenting with an intramuscular, posterior shoulder mass. The aspirate showed a giant cell-rich lesion, admixed with short, plump-looking, spindly cells. There was no overt evidence of malignancy; however, the cell cytology was sufficiently atypical to warrant concern. Subsequent excision revealed a classical pleomorphic lipoma on histology with no evidence of malignancy. CD34 staining by immunohistochemistry further supported the diagnosis. Differential diagnosis and the cytological diagnostic pitfalls of pleomorphic lipomas have been discussed with a review of the literature.
多形性脂肪瘤是一种相对罕见的脂肪细胞肿瘤，主要发生于老年男性的颈部或肩部皮下组织。据我们所知，仅有5例报告显示病变位于肌肉内。我们在此报告1例60岁女性患者，其肩部后方肌肉内出现肿块。抽吸物显示为富含巨细胞的病变，混有短而饱满的梭形细胞。没有明显的恶性证据；然而，细胞细胞学表现足够不典型，值得关注。随后的切除显示组织学上为典型的多形性脂肪瘤，没有恶性证据。免疫组织化学CD34染色进一步支持诊断。通过文献复习讨论了多形性脂肪瘤的鉴别诊断及细胞学诊断陷阱。
