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两例颈部罕见的良性病变,在细针穿刺细胞学检查中被误诊为恶性肿瘤。

Two unusual benign lesions of the neck masquerading as malignancy on fine-needle aspiration cytology.

作者信息

Dundas K E, Wong M P, Suen K C

机构信息

Department of Pathology, Vancouver General Hospital, University of British Columbia, Canada.

出版信息

Diagn Cytopathol. 1995 May;12(3):272-8; discussion 278-9. doi: 10.1002/dc.2840120317.

DOI:10.1002/dc.2840120317
PMID:7621725
Abstract

Two cases of unusual benign tumors of the neck are described, both of which were initially misdiagnosed on cytology as carcinomas. Fine-needle aspiration findings in each case demonstrated a pleomorphic population of cells including bizarre multinucleated giant cells, the latter raising the false impression of malignancy. However, on review the cytological appearances of the tumors, a pleomorphic lipoma and a carotid body tumor, were characteristic. The correct diagnosis in each case would have been made or suggested if the pathologist had been familiar with the cytologic features characteristic of the lesion and the differential diagnosis of the head and neck tumors. In addition, the point is made that adequate clinical information is essential for the pathologist if all relevant conditions are not to be missed in the differential diagnosis.

摘要

本文描述了两例颈部罕见的良性肿瘤,这两例最初在细胞学检查中均被误诊为癌。每例细针穿刺结果均显示细胞形态多样,包括奇异的多核巨细胞,后者给人造成恶性肿瘤的错误印象。然而,回顾肿瘤的细胞学表现,一例为多形性脂肪瘤,另一例为颈动脉体瘤,均具有特征性。如果病理学家熟悉病变的细胞学特征以及头颈部肿瘤的鉴别诊断,那么在每例中都能做出或提示正确的诊断。此外,还指出如果在鉴别诊断中不漏诊所有相关情况,那么足够的临床信息对病理学家来说至关重要。

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Two unusual benign lesions of the neck masquerading as malignancy on fine-needle aspiration cytology.两例颈部罕见的良性病变,在细针穿刺细胞学检查中被误诊为恶性肿瘤。
Diagn Cytopathol. 1995 May;12(3):272-8; discussion 278-9. doi: 10.1002/dc.2840120317.
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引用本文的文献

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Primary Pleomorphic Lipoma of the Parotid Gland with Prominent Myxoid Change: Report of a Rare Case Mimicking Carcinoma Ex Pleomorphic Adenoma on Fine Needle Aspiration Cytology.腮腺原发性多形性脂肪瘤伴显著黏液样变:1例细针穿刺细胞学检查酷似多形性腺瘤癌变的罕见病例报告
Head Neck Pathol. 2020 Mar;14(1):246-249. doi: 10.1007/s12105-018-00998-9. Epub 2019 Jan 4.
2
Pleomorphic Lipoma of the Neck in an Infant: A Rare Clinical Entity.婴儿颈部多形性脂肪瘤:一种罕见的临床病症。
J Indian Assoc Pediatr Surg. 2017 Jul-Sep;22(3):184-186. doi: 10.4103/jiaps.JIAPS_17_17.
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Pleomorphic lipoma: A gentle giant of pathology.
多形性脂肪瘤:病理学中的温和巨物。
J Cytol. 2015 Jul-Sep;32(3):201-3. doi: 10.4103/0970-9371.168904.