Lakshmi V, Rani T S, Sharma S, Mohan V S, Sundaram C, Rao R R, Satyanarayana G
Department of Microbiology, Nizam's Institute of Medical Sciences, Andhra Pradesh, India.
J Clin Microbiol. 1993 May;31(5):1368-9. doi: 10.1128/jcm.31.5.1368-1369.1993.
A case of necrotizing fasciitis of the anterior abdominal wall caused by the zygomycete Apophysomyces elegans in a healthy male following inguinal herniorrhaphy is reported. The portal of entry of the fungus into the incised skin and subcutaneous tissues was probably through either contaminated surgical sutures or postoperative surgical dressings. Broad, aseptate fungal hyphae were seen in the necrosed tissues with an associated necrotizing vasculitis. Extensive tissue debridements and a low dose of amphotericin B were not successful in controlling the rapid invasion of the tissues by the fungus.
报道了1例健康男性在腹股沟疝修补术后由雅致枝孢霉引起的腹壁坏死性筋膜炎病例。真菌进入切开皮肤和皮下组织的途径可能是通过污染的手术缝线或术后手术敷料。在坏死组织中可见宽大、无隔的真菌菌丝,并伴有坏死性血管炎。广泛的组织清创术和低剂量的两性霉素B未能成功控制真菌对组织的快速侵袭。