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使用聚丙烯或聚酯补片进行腹股沟疝修补术后炎症反应与临床结果的比较

The Comparison of Inflammatory Responses and Clinical Results After Groin Hernia Repair Using Polypropylene or Polyester Meshes.

作者信息

Bulbuller N, Kirkil C, Godekmerdan A, Aygen E, Ilhan Y S

机构信息

Department of Surgery, Ataturk Education and Research Hospital, Antalya, Turkey.

Department of Surgery, Medical Faculty, Firat University, Elazig, Turkey ; Firat Universitesi Hastanesi, Genel Cerrahi A.D., 23169 Elazig, Turkey.

出版信息

Indian J Surg. 2015 Dec;77(Suppl 2):283-7. doi: 10.1007/s12262-012-0796-x. Epub 2013 Jan 19.

Abstract

The aim of this study was to compare the clinical results and the inflammatory responses against polypropylene and polyester meshes after groin hernia repair. Ninety patients with unilateral inguinal hernia randomly underwent Shouldice herniorrhaphy or Lichtenstein hernioplasty using polypropylene or polyester meshes. Venous blood samples were collected to evaluate serum interleukin-6 (IL-6) and C-reactive protein (CRP) levels. Postoperative acute and chronic pain and time to attain to normal activities were evaluated. IL-6 levels decreased to preoperative levels in all groups at 48th hour. CRP levels of mesh-implanted groups are significantly higher than preoperative level at 48th hour, while it reduced to preoperative level in Shouldice herniorrhaphy group. Patients treated with mesh repair had less postoperative acute pain and recovered more rapidly than those who underwent Shouldice herniorrhaphy. It was concluded that polypropylene and polyester meshes used in hernia repair caused similar inflammatory responses and that clinical results after groin hernia repair with these prostheses were not significantly different.

摘要

本研究的目的是比较腹股沟疝修补术后使用聚丙烯和聚酯补片的临床结果及炎症反应。90例单侧腹股沟疝患者随机接受使用聚丙烯或聚酯补片的Shouldice疝修补术或Lichtenstein疝修补术。采集静脉血样本以评估血清白细胞介素-6(IL-6)和C反应蛋白(CRP)水平。评估术后急性和慢性疼痛以及恢复正常活动的时间。所有组在第48小时时IL-6水平降至术前水平。补片植入组在第48小时时CRP水平显著高于术前水平,而Shouldice疝修补术组则降至术前水平。接受补片修补治疗的患者术后急性疼痛较轻,比接受Shouldice疝修补术的患者恢复得更快。得出的结论是,疝修补术中使用的聚丙烯和聚酯补片引起的炎症反应相似,使用这些假体进行腹股沟疝修补后的临床结果无显著差异。

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