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巨大肠系膜硬纤维瘤的姑息性切除术

Palliative Resection of a Giant Mesenteric Desmoid Tumor.

作者信息

Sugrue Jeremy J, Cohen Stephanie B, Marshall Roland M, Riker Adam I

机构信息

Department of Surgery, University of Illinois at Chicago, Chicago, IL.

Department of Surgery, Advocate Cancer Institute, Advocate Christ Medical Center, Oak Lawn, IL.

出版信息

Ochsner J. 2015 Winter;15(4):468-72.

Abstract

BACKGROUND

Desmoid tumors are relatively uncommon tumors, and those occurring sporadically and in an intraabdominal location are especially rare. Although desmoid tumors have a benign histologic appearance and lack the ability to metastasize, they can invade locally, often aggressively, grow to large sizes, and recur repeatedly.

CASE REPORT

We present the case of a symptomatic, giant mesenteric desmoid tumor discovered incidentally during workup for the patient's previous history of lung cancer. The patient elected to undergo palliative resection of the tumor because of persistent and unrelenting abdominal pain.

CONCLUSION

Because of the rarity of the disease, no clear evidence-based guidelines exist for the treatment of sporadic mesenteric desmoid tumors. Review of the available literature suggests that surgical resection with negative margins is a reasonable approach for patients with symptomatic tumors.

摘要

背景

韧带样瘤是相对罕见的肿瘤,散发性且发生于腹腔内的韧带样瘤尤为罕见。尽管韧带样瘤具有良性的组织学表现且无转移能力,但它们可局部侵袭,常呈侵袭性生长,体积增大,并反复复发。

病例报告

我们报告一例有症状的巨大肠系膜韧带样瘤病例,该病例是在对患者既往肺癌病史进行检查时偶然发现的。由于持续性腹痛且疼痛不断加剧,患者选择接受肿瘤姑息性切除术。

结论

由于该疾病罕见,对于散发性肠系膜韧带样瘤的治疗尚无明确的循证指南。对现有文献的回顾表明,切缘阴性的手术切除是有症状肿瘤患者的一种合理治疗方法。

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本文引用的文献

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Mesenteric fibromatosis.肠系膜纤维瘤病
Int J Colorectal Dis. 2014 Dec;29(12):1445-51. doi: 10.1007/s00384-014-1995-7. Epub 2014 Aug 21.
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Long-term outcomes for desmoid tumors treated with radiation therapy.放射治疗韧带样瘤的长期疗效。
Int J Radiat Oncol Biol Phys. 2008 Jun 1;71(2):441-7. doi: 10.1016/j.ijrobp.2007.10.013. Epub 2008 Feb 20.

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