Blumetti Jennifer, Abcarian Herand
Jennifer Blumetti, Herand Abcarian, Division of Colon and Rectal Surgery, John H. Stroger Hospital of Cook County, Chicago, IL 60612, United States.
World J Gastrointest Surg. 2015 Dec 27;7(12):378-83. doi: 10.4240/wjgs.v7.i12.378.
Anastomotic leak continues to be a dreaded complication after colorectal surgery, especially in the low colorectal or coloanal anastomosis. However, there has been no consensus on the management of the low colorectal anastomotic leak. Currently operative procedures are reserved for patients with frank purulent or feculent peritonitis and unstable vital signs, and vary from simple fecal diversion with drainage to resection of the anastomosis and closure of the rectal stump with end colostomy (Hartmann's procedure). However, if the patient is stable, and the leak is identified days or even weeks postoperatively, less aggressive therapeutic measures may result in healing of the leak and salvage of the anastomosis. Advances in diagnosis and treatment of pelvic collections with percutaneous treatments, and newer methods of endoscopic therapies for the acutely leaking anastomosis, such as use of the endosponge, stents or clips, have greatly reduced the need for surgical intervention in selected cases. Diverting ileostomy, if not already in place, may be considered to reduce fecal contamination. For subclinical leaks or those that persist after the initial surgery, endoluminal approaches such as injection of fibrin sealant, use of endoscopic clips, or transanal closure of the very low anastomosis may be utilized. These newer techniques have variable success rates and must be individualized to the patient, with the goal of treatment being restoration of gastrointestinal continuity and healing of the anastomosis. A review of the treatment of low colorectal anastomotic leaks is presented.
吻合口漏仍然是结直肠手术后令人恐惧的并发症,尤其是在低位结直肠或结肠肛管吻合术中。然而,对于低位结直肠吻合口漏的处理尚无共识。目前,手术治疗仅适用于伴有明显脓性或粪性腹膜炎且生命体征不稳定的患者,手术方式从简单的粪便转流加引流到吻合口切除及直肠残端闭合并行结肠造口术(哈特曼手术)不等。然而,如果患者病情稳定,且在术后数天甚至数周才发现吻合口漏,采取较保守的治疗措施可能会使漏口愈合,吻合口得以保留。经皮治疗盆腔积液在诊断和治疗方面的进展,以及针对急性吻合口漏的新型内镜治疗方法,如使用内镜海绵、支架或夹子,已大大减少了部分病例的手术干预需求。如果尚未行转流性回肠造口术,可考虑施行以减少粪便污染。对于亚临床漏或初次手术后持续存在的漏口,可采用腔内治疗方法,如注射纤维蛋白封闭剂、使用内镜夹子或经肛门闭合极低位置的吻合口。这些新技术的成功率各不相同,必须根据患者个体情况进行选择,治疗目标是恢复胃肠道连续性及吻合口愈合。本文对低位结直肠吻合口漏的治疗进行综述。