Sato Taishi, Nakashima Yasuharu, Komiyama Keisuke, Yamamoto Takuaki, Motomura Goro, Iwamoto Yukihide
Department of Orthopaedic Surgery, Kyushu University, Fukuoka City, Fukuoka, Japan.
J Arthroplasty. 2016 Jun;31(6):1228-1232. doi: 10.1016/j.arth.2015.11.034. Epub 2015 Dec 2.
Hydroxyapatite (HA) has been applied to joint prostheses as a bioactive coating to prolong their durability. However, HA benefits for cup survival in total hip arthroplasty (THA) remain controversial. In this study, we compared the survival of cups with and without HA coating during a minimum follow-up of 18 years.
In total, 183 THA cases in 163 patients were analyzed, including 73 cups with HA coating (HA(+) group) and 110 without HA coating (HA(-) group); otherwise, the cups had identical titanium-sprayed rough surfaces and were fixed with screws. In both groups, the same conventional polyethylene liners were applied. Zirconia and alumina ceramic heads were used in the HA(+) and HA(-) groups, respectively. We retrospectively analyzed cup survival based on cup revision for any reason or aseptic loosening as end points.
In total, 7 and 8 revisions were performed in the HA(-) and HA(+) groups with survival rates of 86.3% and 90.1%, respectively. Among them, 3 cups in the HA(-) group and 1 cup in the HA(+) group were revised for aseptic loosening in 20 years (survival rates 94.1% and 98.7%, respectively). No significant difference was detected in cup survival rates between the groups based on both end points. There were no stem revisions during the observation period.
The results suggested that HA coating did not have either beneficial or adverse effects on the long-term cup survival in primary cementless THA.
羟基磷灰石(HA)已作为生物活性涂层应用于关节假体,以延长其使用寿命。然而,HA对全髋关节置换术(THA)中髋臼杯生存率的益处仍存在争议。在本研究中,我们比较了有HA涂层和无HA涂层的髋臼杯在至少18年随访期内的生存率。
共分析了163例患者的183例THA病例,其中73个髋臼杯有HA涂层(HA(+)组),110个无HA涂层(HA(-)组);除此之外,两组髋臼杯均有相同的钛喷涂粗糙表面,并用螺钉固定。两组均使用相同的传统聚乙烯内衬。HA(+)组和HA(-)组分别使用氧化锆和氧化铝陶瓷股骨头。我们以因任何原因进行的髋臼杯翻修或无菌性松动为终点,回顾性分析髋臼杯生存率。
HA(-)组和HA(+)组分别进行了7次和8次翻修,生存率分别为86.3%和90.1%。其中,HA(-)组有3个髋臼杯和HA(+)组有1个髋臼杯在20年内因无菌性松动进行了翻修(生存率分别为94.1%和98.7%)。基于这两个终点,两组髋臼杯生存率无显著差异。观察期内无股骨柄翻修病例。
结果表明,HA涂层对初次非骨水泥型THA中髋臼杯的长期生存率既无有益影响也无不利影响。