Nakashima Yasuharu, Sato Taishi, Yamamoto Takuaki, Motomura Goro, Ohishi Masanobu, Hamai Satoshi, Akiyama Mio, Hirata Masanobu, Hara Daisuke, Iwamoto Yukihide
Department of Orthopaedic Surgery, Kyushu University, 1-3-3 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan,
J Orthop Sci. 2013 Nov;18(6):962-8. doi: 10.1007/s00776-013-0456-4. Epub 2013 Aug 21.
The purpose of this study was to report results at a minimum of 10 years for hydroxyapatite (HA) coating on the titanium arc-sprayed cementless total hip arthroplasty (THA) and to evaluate the impact of cross-linked polyethylene (XLPE) on implant longevity.
A total of 131 consecutive primary THAs in 123 patients using an AMS acetabular cup and a PerFix HA stem were retrospectively reviewed. Conventional PE was used for 62 hips (CPE group) and cross-linked PE for 69 hips (XLPE group), with mean follow-up periods of 13 and 11.5 years, respectively. These patients were reviewed using the Japanese Orthopaedic Association (JOA) Hip Score and evaluated in terms of PE wear, osteolysis, and implant survival.
The JOA score improved from 42.6 to 83.9 points at the final follow-up. The mean wear rate of 0.12 mm/year in the CPE group was significantly greater than that of XLPE at 0.007 mm/year. In the CPE group, ten (16.1 %) and two (3.2 %) hips, respectively, underwent PE exchange due to severe wear and acetabular revision due to loosening associated with osteolysis. Three patients had revision in the XLPE group: one cup for aseptic loosening, one PE for recurrent dislocation, and one stem for neck fracture. No evident osteolysis was seen in the XLPE group. Kaplan-Meier survivorship with any revision as the end point shows that the 12-year survival rate was 97.7 % for cups, 93.8 % for PE liners, and 99.2 % for stems. Multivariate analysis revealed that the use of XLPE significantly reduced the risk of revision, with the odds ratio (OR) of 4.3.
AMS and PerFix HA components in this series show excellent implant fixation; however, high rates of PE wear and subsequent osteolysis were limiting factors in long-term success. Low wear rates with XLPE suggest improved implant longevity.
本研究旨在报告钛电弧喷涂无骨水泥全髋关节置换术(THA)中羟基磷灰石(HA)涂层至少10年的结果,并评估交联聚乙烯(XLPE)对植入物使用寿命的影响。
回顾性分析了123例患者连续进行的131例初次THA,使用的是AMS髋臼杯和PerFix HA柄。62髋使用传统聚乙烯(CPE组),69髋使用交联聚乙烯(XLPE组),平均随访时间分别为13年和11.5年。使用日本骨科学会(JOA)髋关节评分对这些患者进行评估,并从聚乙烯磨损、骨溶解和植入物存活情况方面进行评价。
末次随访时JOA评分从42.6分提高到83.9分。CPE组平均磨损率为每年0.12mm,显著高于XLPE组的每年0.007mm。在CPE组中,分别有10髋(16.1%)因严重磨损进行了聚乙烯置换,2髋(3.2%)因与骨溶解相关的松动进行了髋臼翻修。XLPE组有3例患者进行了翻修:1例髋臼杯因无菌性松动,1例聚乙烯内衬因复发性脱位,1例柄因颈部骨折。XLPE组未见明显骨溶解。以任何翻修为终点的Kaplan-Meier生存率显示,髋臼杯12年生存率为97.7%,聚乙烯内衬为93.8%,柄为99.2%。多因素分析显示,使用XLPE显著降低了翻修风险,优势比(OR)为4.3。
本系列中的AMS和PerFix HA组件显示出优异的植入物固定效果;然而,聚乙烯的高磨损率及随后的骨溶解是长期成功的限制因素。XLPE的低磨损率表明植入物使用寿命得到改善。