Huang Peiwu, Li Xuan, Liu Wei, Liu Jianjun
Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China; Email:
Zhonghua Yu Fang Yi Xue Za Zhi. 2015 Sep;49(9):844-8.
Trichloroethylene (TCE) is a widely used organic solvent and an important industrial material. Due to mass production and use, and improper waste disposal, TCE has become a common environmental contaminant, so there is a wide range of occupationally and environmentally exposed population. Occupational and environmental exposure to TCE can produce toxic effects on multiple organs and systems. This paper is a review of the immunotoxicity, reproductive toxicity, neurotoxicity, teratogenic effect and other non-carcinogenic toxic effects of TCE from the aspects of epidemiological study, experimental evidence on animals and toxic mechanisms.
三氯乙烯（TCE）是一种广泛使用的有机溶剂和重要的工业原料。由于大规模生产和使用，以及废物处理不当，TCE已成为一种常见的环境污染物，因此存在广泛的职业和环境暴露人群。职业和环境暴露于TCE可对多个器官和系统产生毒性作用。本文从流行病学研究、动物实验证据和毒性机制等方面综述了TCE的免疫毒性、生殖毒性、神经毒性、致畸作用及其他非致癌毒性作用。
