Caraiani Cosmin-Nicolae, Dan Marian, Fenesan Diana-Ioana, Badea Radu
Department of Medical Imaging, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Department of Ultrasonography/Medical Imaging, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Clujul Med. 2015;88(4):438-48. doi: 10.15386/cjmed-414. Epub 2015 Nov 15.
Imaging procedures play a fundamental role in the therapeutic management of focal liver lesions. The goals of imaging are to detect and correctly characterize focal liver lesions. This review highlights the performances of newer, liver-specific, contrast media in the diagnosis of focal liver lesions, particularly Gd-EOB-DTPA (Primovist), the most frequently used liver specific contrast media. It has been shown, in different papers, that Gd-EOB-DTPA has better performances compared to either triphasic contrast enhanced computed tomography or dynamic MRI in both detection and characterization of hepatocellular carcinoma on the cirrhotic liver. Therefore liver MRI with Primovist is considered, in many centers, the "state-of-the-art" imaging examination of the liver before surgery or liver transplantation. Gd-EOB-DTPA is also useful in the differential diagnosis of benign hypervascular focal liver lesions such as adenomas or focal nodular hyperplasias.
成像程序在肝脏局灶性病变的治疗管理中发挥着重要作用。成像的目的是检测并正确鉴别肝脏局灶性病变。本综述重点介绍了新型肝脏特异性对比剂在肝脏局灶性病变诊断中的性能，尤其是钆塞酸二钠（普美显），这是最常用的肝脏特异性对比剂。不同文献表明，在肝硬化肝脏上肝细胞癌的检测和鉴别方面，钆塞酸二钠相比三相对比增强计算机断层扫描或动态磁共振成像具有更好的性能。因此，在许多中心，使用普美显的肝脏磁共振成像被视为手术或肝移植前肝脏的“先进”成像检查。钆塞酸二钠在鉴别诊断良性富血供肝脏局灶性病变（如腺瘤或局灶性结节性增生）方面也很有用。
