Orimo H, Yaegashi Y, Hosoi T, Fukushima Y, Onoda T, Hashimoto T, Sakata K
Kenkoin Clinic, Chuo-ku, Tokyo, Japan.
Department of Hygiene and Preventive Medicine, School of Medicine, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan.
Osteoporos Int. 2016 May;27(5):1777-84. doi: 10.1007/s00198-015-3464-8. Epub 2016 Jan 5.
We estimated the number of hip fracture patients in 2012 in Japan and investigated the trends in incidence during a 25-year period from 1987 to 2012. Despite the increasing number of patients, the incidence of hip fracture in both men and women aged 70-79 years showed the possibility of decline.
The objectives of this study were to estimate the number of hip fracture patients in 2012, to investigate the trends in incidence during a 25-year period from 1987 to 2012, and to determine the regional differences in Japan.
Data were collected through a nationwide survey based on hospitals by a mail-in survey. Hip fracture incidences by sex and age and standardized incidence ratios by region were calculated.
The estimated numbers of new hip fracture patients in 2012 were 175,700 in total (95 % CI 170,300-181,100), 37,600 (36,600-38,600) for men and 138,100 (134,300-141,900) for women. The incidence rates in both men and women aged 70-79 years were the lowest in the 20-year period from 1992 to 2012. The incidence was higher in western areas of Japan than that in eastern areas in both men and women; however, the difference in the incidence of hip fracture between western and eastern areas is becoming smaller.
Despite the increasing number of new patients, the incidence of hip fracture in both men and women aged 70-79 years showed the possibility of decline. The exact reasons for this are unknown, but various drugs for improving bone mineral density or preventing hip fracture might have influenced the results. A decrease in the differences in nutrient intake levels might explain some of the change in regional differences in Japan.
我们估算了2012年日本髋部骨折患者的数量,并调查了1987年至2012年这25年间的发病率趋势。尽管患者数量在增加,但70至79岁男性和女性的髋部骨折发病率显示出下降的可能性。
本研究的目的是估算2012年髋部骨折患者的数量,调查1987年至2012年这25年间的发病率趋势,并确定日本的地区差异。
通过基于医院的全国性邮寄调查收集数据。计算了按性别和年龄划分的髋部骨折发病率以及按地区划分的标准化发病率。
2012年新髋部骨折患者的估算总数为175,700例(95%置信区间170,300 - 181,100),男性为37,600例(36,600 - 38,600),女性为138,100例(134,300 - 141,900)。在1992年至2012年的20年间,70至79岁男性和女性的发病率均为最低。日本西部地区男性和女性的发病率均高于东部地区;然而,东西部地区髋部骨折发病率的差异正在缩小。
尽管新患者数量在增加,但70至79岁男性和女性的髋部骨折发病率显示出下降的可能性。其确切原因尚不清楚,但各种用于改善骨密度或预防髋部骨折的药物可能影响了结果。营养摄入水平差异的减小可能解释了日本地区差异变化的部分原因。