Whitehouse M R, Parry M C, Konan S, Duncan C P
University of Bristol, Southmead Hospital, Bristol, BS10 5NB, UK.
Royal Orthopaedic Hospital NHS Foundation Trust, Bristol Road South, Birmingham, B31 2AP, UK.
Bone Joint J. 2016 Jan;98-B(1 Suppl A):27-30. doi: 10.1302/0301-620X.98B1.36294.
Periprosthetic joint infection (PJI) complicates between 0.5% and 1.2% primary total hip arthroplasties (THAs) and may have devastating consequences. The traditional assessment of patients suffering from PJI has involved the serological study of inflammatory markers and microbiological analysis of samples obtained from the joint space. Treatment has involved debridement and revision arthroplasty performed in either one or two stages. We present an update on the burden of PJI, strategies for its diagnosis and treatment, the challenge of resistant organisms and the need for definitive evidence to guide the treatment of PJI after THA.
人工关节周围感染（PJI）在0.5%至1.2%的初次全髋关节置换术（THA）中会出现并发症，且可能产生严重后果。对患有PJI的患者进行的传统评估包括炎症标志物的血清学研究以及从关节腔获取的样本的微生物学分析。治疗方法包括一期或二期进行清创和翻修关节成形术。我们提供了关于PJI负担、其诊断和治疗策略、耐药菌的挑战以及获得确凿证据以指导THA后PJI治疗的必要性的最新情况。
