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胃旁路术后非胰岛素瘤性高胰岛素血症低血糖症的修正手术治疗方案

PROPOSAL OF A REVISIONAL SURGERY TO TREAT NON-INSULINOMA HYPERINSULINEMIC HYPOGLICEMIA POSTGASTRIC BYPASS.

作者信息

Sampaio-Neto José, Branco-Filho Alcides José, Nassif Luis Sérgio, Nassif André Thá, De Masi Flávia David João, Ximenez Daniele Rezende

机构信息

Santa Casa de Misericórdia Hospital, Curitiba, PR, Brazil.

出版信息

Arq Bras Cir Dig. 2015 Nov-Dec;28(4):278-81. doi: 10.1590/S0102-6720201500040015.

Abstract

BACKGROUND

Hyperinsulinemic hypoglicemia with severe neuroglycopenic symptoms has been identified as a late and rare complication in patients submitted to Roux-en-Y gastric bypass. However, the potential gravity of its manifestations requires effective treatment of this condition. The absence of treatment makes it necessary to develop more effective clinical or surgical methods.

AIM

To present one surgical option to revisional surgery in the treatment of hyperinsulinemic hypoglicemia Methods : The procedure consists in reconstituting alimentary transit through the duodenum and proximal jejunum, while keeping the restrictive part of the gastric bypass. As an additional strategy to maintain weight loss, is realized gastric fundus resection, aiming to suppress ghrelin production more effectively.

RESULTS

It was used in three patients with successful results in one year of follow-up.

CONCLUSION

The procedure to reconstruct the food transit through the duodenum and proximal jejunum, keeping the restrictive component of gastric bypass in the treatment of hyperinsulinemic hypoglycemia showed good initial results and validated its application in other cases with this indication.

摘要

背景

高胰岛素血症性低血糖伴严重神经低血糖症状已被确定为接受Roux-en-Y胃旁路手术患者的一种晚期且罕见的并发症。然而,其表现的潜在严重性需要对这种情况进行有效治疗。缺乏治疗方法使得有必要开发更有效的临床或手术方法。

目的

介绍一种用于治疗高胰岛素血症性低血糖的翻修手术的手术选择。

方法

该手术包括重建经十二指肠和空肠近端的消化道通路,同时保留胃旁路手术的限制性部分。作为维持体重减轻的一项额外策略,实施胃底切除术,旨在更有效地抑制胃饥饿素的产生。

结果

该手术应用于3例患者,随访1年效果良好。

结论

重建经十二指肠和空肠近端的食物通路并保留胃旁路手术的限制性部分来治疗高胰岛素血症性低血糖的手术,初步结果良好,并证实了其在其他有此适应症的病例中的应用价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434a/4755183/1d75f54e78b0/0102-6720-abcd-28-04-00278-gf01.jpg

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