Rogerio Wesley Pereira, Prado Thiago Nascimento do, Souza Fernanda Mattos de, Pinheiro Jair dos Santos, Rodrigues Patrícia Marques, Sant'anna Amanda Pissinate do Nascimento, Jesus Kássia Gomes de, Cerutti Junior Crispim, Lima Rita de Cássia Duarte, Maciel Ethel Leonor Noia
Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, Brasil.
Departamento de Vigilância Ambiental e Epidemiológica, Secretaria Municipal de Saúde de Manaus, Manaus, Brasil.
Cad Saude Publica. 2015 Oct;31(10):2199-210. doi: 10.1590/0102-311X00152414.
This article aimed to determine the prevalence of latent Mycobacterium tuberculosis infection and associated factors in community health workers (CHW) in Brazil, using two cutoff points for the tuberculin skin test (5mm and 10mm). This was a cross-sectional study with data on gender, age, BCG scar, working in a primary care unit (PCU), having a household contact with tuberculosis (TB), alcohol consumption, previous tuberculin skin test (TST), smoking, time on the job as CHW, and comorbidities. Logistic regression was used to estimate odds ratios (OR) and to control for confounding. TST was applied and read after 48-72 hours. Prevalence rates were 57.88% and 37.3%, respectively, for the 5mm and 10mm TST cutoffs. Variables that remained associated with positive TST using the 10mm cutoff were working in a primary care unit that had implemented a Tuberculosis Control Program (TCP) and history of household contact with TB. Variables associated with the 5mm cutoff were working in a primary care unit with a TCP. Necessary actions at the local level include awareness-raising and strengthening of continuing education.
本文旨在利用结核菌素皮肤试验的两个临界点（5毫米和10毫米），确定巴西社区卫生工作者中潜伏性结核分枝杆菌感染的患病率及相关因素。这是一项横断面研究，收集了有关性别、年龄、卡介苗疤痕、在基层医疗单位工作、有结核病家庭接触史、饮酒、既往结核菌素皮肤试验（TST）、吸烟、担任社区卫生工作者的工作时间以及合并症的数据。采用逻辑回归估计比值比（OR）并控制混杂因素。TST在48 - 72小时后进行应用和读取。对于5毫米和10毫米的TST临界点，患病率分别为57.88%和37.3%。使用10毫米临界点时，与TST阳性仍相关的变量是在实施了结核病控制项目（TCP）的基层医疗单位工作以及有结核病家庭接触史。与5毫米临界点相关的变量是在设有TCP的基层医疗单位工作。地方层面的必要行动包括提高认识和加强继续教育。
