Venkataramani Krithika, Mestha Lalit K, Ramachandra L, Prasad S S, Kumar Vijay, Raja Priyanka J
Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:2022-5. doi: 10.1109/EMBC.2015.7318783.
Screening for breast cancer enables early detection by which curative treatment can be possible. While mammography is the current gold standard for screening, it has low sensitivity in younger women and its harmful X-rays in frequent screening can increase the risk of cancer. Incidence rates are rising in younger women, causing a relook at thermography for low cost and non-harmful screening. In this paper, thermography is compared to mammography correlated with sono-mammography in 65 FNAC/biopsy proven cancer subjects in India. Thermography is comparable to mammography correlated with sono-mammography, having 94% and 95% sensitivity, respectively. A novel semi-automated thermographic tumor detection and location algorithm used in this paper also provides 97% sensitivity. This shows the promise of automated thermographic screening for reaching large populations in a cost effective manner in low resource settings in countries like India. Further studies in a large scale need to be done to evaluate the specificity to enable such solutions.
乳腺癌筛查能够实现早期检测，从而有可能进行治愈性治疗。虽然乳腺钼靶摄影是目前筛查的金标准，但它在年轻女性中的敏感性较低，且频繁筛查时其有害的X射线会增加患癌风险。年轻女性的发病率正在上升，这促使人们重新审视热成像技术，因其成本低且无危害。在本文中，对印度65名经细针穿刺抽吸活检（FNAC）/活检证实为癌症的受试者进行了热成像与乳腺钼靶摄影以及超声钼靶摄影相关性的比较。热成像与乳腺钼靶摄影以及超声钼靶摄影具有可比性，敏感性分别为94%和95%。本文中使用的一种新型半自动热成像肿瘤检测和定位算法的敏感性也达到了97%。这表明在印度等资源匮乏的国家，自动热成像筛查有望以具有成本效益的方式覆盖大量人群。需要进行大规模的进一步研究以评估其特异性，从而实现此类解决方案。
