Bruge Sophie, Simon Antoine, Lederlin Mathieu, Betancur Julian, Hernandez Alfredo, Donal Erwan, Leclercq Christophe, Garreau Mireille
Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:2391-4. doi: 10.1109/EMBC.2015.7318875.
Cardiac Resynchronization Therapy (CRT) has been validated as an efficient treatment for selected patients suffering from heart failure with cardiac dyssynchrony. In case of bi-ventricular stimulation, the response to the therapy may be improved by an optimal choice of the left ventricle (LV) pacing sites. The characterization of LV properties to select the best candidate sites and to precise their access modes would be useful for the clinician in pre- and per-operative stages. For that purpose, we propose a new pre-operative analysis solution integrating previously developed multi-modal data registration methods and a new segmentation process of their coronary venous access. Moreover, a novel visualization interface is proposed to help the clinician to visualize the most relevant pacing sites and their access during the implantation in the operating room. This work is illustrated on real CRT data patients.
心脏再同步治疗(CRT)已被证实是治疗某些伴有心脏不同步的心力衰竭患者的有效方法。在双心室刺激的情况下,通过优化选择左心室(LV)起搏部位可改善治疗反应。在术前和术中阶段,对左心室特性进行表征以选择最佳候选部位并明确其进入方式,将对临床医生有所帮助。为此,我们提出了一种新的术前分析解决方案,该方案整合了先前开发的多模态数据配准方法以及一种新的冠状静脉进入分割过程。此外,还提出了一种新颖的可视化界面,以帮助临床医生在手术室植入过程中可视化最相关的起搏部位及其进入方式。这项工作通过CRT真实数据患者进行了说明。