Liu X X, Chai G H, Qu H E, Lan N
Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:2493-6. doi: 10.1109/EMBC.2015.7318898.
The lack of reliable sensory feedback has been one of the barriers in prosthetic hand development. Restoring sensory function from prosthetic hand to amputee remains a great challenge to neural engineering. In this paper, we present the development of a sensory feedback system based on the phenomenon of evoked tactile sensation (ETS) at the stump skin of residual limb induced by transcutaneous electrical nerve stimulation (TENS). The system could map a dynamic pattern of stimuli to an electrode placed on the corresponding projected finger areas on the stump skin. A pressure transducer placed at the tip of prosthetic fingers was used to sense contact pressure, and a high performance DSP processor sampled pressure signals, and calculated the amplitude of feedback stimulation in real-time. Biphasic and charge-balanced current pulses with amplitude modulation generated by a multi-channel laboratory stimulator were delivered to activate sensory nerves beneath the skin. We tested this sensory feedback system in amputee subjects. Preliminary results showed that the subjects could perceive different levels of pressure at the tip of prosthetic finger through evoked tactile sensation (ETS) with distinct grades and modalities. We demonstrated the feasibility to restore the perceptual sensation from prosthetic fingers to amputee based on the phenomenon of evoked tactile sensation (ETS) with TENS.
缺乏可靠的感觉反馈一直是假手发展的障碍之一。将假手的感觉功能恢复到截肢者身上,对神经工程来说仍然是一个巨大的挑战。在本文中,我们展示了一种基于经皮电神经刺激(TENS)在残肢残端皮肤诱发的触觉诱发感觉(ETS)现象的感觉反馈系统的开发。该系统可以将刺激的动态模式映射到放置在残端皮肤上相应投射手指区域的电极上。放置在假手指尖端的压力传感器用于感知接触压力,高性能DSP处理器对压力信号进行采样,并实时计算反馈刺激的幅度。由多通道实验室刺激器产生的具有幅度调制的双相和电荷平衡电流脉冲被输送以激活皮肤下的感觉神经。我们在截肢者受试者中测试了这种感觉反馈系统。初步结果表明,受试者可以通过具有不同等级和模式的触觉诱发感觉(ETS)感知假手指尖端的不同压力水平。我们证明了基于TENS的触觉诱发感觉(ETS)现象将假手指的感知感觉恢复到截肢者身上的可行性。