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诊断指导皮肤真菌感染的治疗。

Diagnosis directs treatment in fungal infections of the skin.

作者信息

Panthagani Anusha P, Tidman Michael J

出版信息

Practitioner. 2015 Oct;259(1786):25-9, 3.

Abstract

Dermatophyte fungi are confined to the keratin layer of the epidermis and include three genera: Microsporum, Epidermophyton and Trichophyton. These infections can be transmitted by human contact (anthropophilic), from the soil (geophilic) and by animal (zoophilic) spread. Dermatophyte infections usually present as an erythematous, scaly eruption, which may or may not be itchy. Asymmetry is an important clinical clue to fungal infection, as is annular morphology. Examination under ultraviolet (Wood's light) can be helpful. The gold standard for diagnosing cutaneous fungal infections is microscopy and culture of scale, hair or nail, and a definite diagnosis is desirable before commencing treatment, especially with oral therapy. Any dermatophyte species affecting the body can affect the hands. The most common organism is T. rubrum. Tinea corporis infection affects the trunk mainly in children and adolescents, and all genera of dermatophyte can cause it. Tinea cruris infection involves the groin region and is more common in men than women. T. rubrum is the most common causative dermatophyte. The clinical features of tinea capitis include patchy hair loss with varying degrees of scale, erythema and pustules. Infected hairs tend to break at the base, leaving stubble. Occasionally, there is invasion of the visible epidermis, resulting in a boggy, painful swelling with associated alopecia and regional lymphadenopathy known as a kerion.

摘要

皮肤癣菌局限于表皮角质层,包括三个属:小孢子菌属、表皮癣菌属和毛癣菌属。这些感染可通过人与人接触传播(嗜人型)、由土壤传播(嗜土型)以及通过动物传播(嗜动物型)。皮肤癣菌感染通常表现为红斑鳞屑性皮疹,可能伴有或不伴有瘙痒。不对称是真菌感染的重要临床线索,环形形态也是如此。在紫外线(伍德灯)下检查可能会有帮助。诊断皮肤真菌感染的金标准是对鳞屑、毛发或指甲进行显微镜检查和培养,在开始治疗前,尤其是口服治疗前,需要明确诊断。任何影响身体的皮肤癣菌种类都可能影响手部。最常见的病原体是红色毛癣菌。体癣感染主要影响儿童和青少年的躯干,所有皮肤癣菌属均可引起。股癣感染累及腹股沟区域,男性比女性更常见。红色毛癣菌是最常见的致病皮肤癣菌。头癣的临床特征包括斑片状脱发,伴有不同程度的鳞屑、红斑和脓疱。受感染的毛发往往在根部折断,留下残茬。偶尔,可见表皮会受到侵犯,导致肿胀、疼痛,伴有脱发和局部淋巴结病,称为脓癣。

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