Turk J Med Sci. 2015;45(5):1004-9. doi: 10.3906/sag-1406-146.
This review highlight the similarities in the pathogenesis between Alzheimer disease and age-related macular degeneration. All studies published between 1990 and 2014 were reviewed to identify the common pathological pathways. Alzheimer disease and age-related macular degeneration share common features such as vitronectin and amyloid-β accumulation, increased oxidative stress, and apolipoprotein and complement activation pathways, which are reviewed as histologic and immunologic common features.
这篇综述强调了阿尔茨海默病和年龄相关性黄斑变性之间在发病机制上的相似性。为了确定共同的病理途径，我们对 1990 年至 2014 年间发表的所有研究进行了回顾。阿尔茨海默病和年龄相关性黄斑变性具有共同的特征，如玻璃连蛋白和淀粉样β 积累、氧化应激增加以及载脂蛋白和补体激活途径等，这些特征在组织学和免疫学方面进行了综述。
