Fraile Rodrigo Jesús José, Cisneros Ana I, Obón Jesús, Yus Carmen, Crovetto Rafael, Crovetto Miguel A, Whyte Jaime
Servicio de Otorrinolaringología, Hospital Universitario Miguel Servet, Zaragoza, España.
Departamento de Anatomía e Histología Humanas, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, España.
Acta Otorrinolaringol Esp. 2016 Jul-Aug;67(4):226-32. doi: 10.1016/j.otorri.2015.09.006. Epub 2015 Dec 28.
To analyze the ontogeny of the superior semicircular canal and tegmen tympani and determine if there are common embryological factors explaining both associated dehiscence.
We analyzed 77 human embryological series aged between 6 weeks and newborn. Preparations were serially cut and stained with Masson's trichrome technique.
The tegmental prolongation of tegmen tympani and superior semicircular canal originate from the same structure, the otic capsule, and have the same type of endochondral ossification; while the extension of the squamous prolongation of tegmen tympani runs from the temporal squama and ossification is directly of intramembranous type. The nuclei of ossification of the superior and external semicircular canals and accessory of tegmen collaborate in the ossification of the tegmental extension and by growth extend to the tegmental prolongation. This fact plus the fact that both structures share a common layer of external periosteum could explain the coexistence of lack of bone coverage in tegmen and superior semicircular canal.
The development of the semicircular canal and tegmen tympani could explain the causes of the association of both dehiscences.
分析上半规管和鼓室盖的个体发育过程，并确定是否存在共同的胚胎学因素来解释两者相关的骨质缺损。
我们分析了77例年龄在6周龄至新生儿之间的人类胚胎标本系列。标本进行连续切片，并用马松三色染色技术染色。
鼓室盖的被盖部延长和上半规管起源于同一结构，即耳囊，并且具有相同类型的软骨内成骨；而鼓室盖鳞状部延长的延伸部分起自颞鳞，其骨化直接为膜内成骨类型。上半规管和外侧半规管的骨化核以及鼓室盖的附属结构共同参与被盖部延伸的骨化，并通过生长延伸至被盖部延长。这一事实加上两者结构共享一层外骨膜这一事实，可以解释鼓室盖和上半规管缺乏骨质覆盖的共存现象。
半规管和鼓室盖的发育可以解释两者骨质缺损相关性的原因。
