Adams Daniel J, Susi Apryl, Erdie-Lalena Christine R, Gorman Gregory, Hisle-Gorman Elizabeth, Rajnik Michael, Elrod Marilisa, Nylund Cade M
Department of Pediatrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, USA.
J Autism Dev Disord. 2016 May;46(5):1636-42. doi: 10.1007/s10803-015-2689-x.
Acute otitis media (AOM) symptoms can be masked by communication deficits, common to children with autism spectrum disorders (ASD). We sought to evaluate the association between ASD and otitis media. Using ICD-9-CM diagnostic codes, we performed a retrospective case-cohort study comparing AOM, and otitis-related diagnoses among children with and without ASD. Children with ASD had a significantly increased rate of AOM, otitis media with effusion, otorrhea, and PE tube placement. Children with ASD were more than twice as likely to develop mastoiditis, and to undergo mastoidectomy and tympanoplasty. Children with ASD are more likely to have middle ear infections and otitis-related complications, highlighting the importance of routine middle ear examinations and close attention to hearing impairment in this population.
急性中耳炎(AOM)的症状可能会被自闭症谱系障碍(ASD)儿童常见的沟通障碍所掩盖。我们试图评估ASD与中耳炎之间的关联。利用国际疾病分类第九版临床修正本(ICD-9-CM)诊断编码,我们进行了一项回顾性病例队列研究,比较了患有和未患有ASD的儿童的AOM及与中耳炎相关的诊断。患有ASD的儿童患AOM、中耳积液、耳漏和置放鼓膜通气管的发生率显著增加。患有ASD的儿童发生乳突炎、接受乳突切除术和鼓室成形术的可能性是常人的两倍多。患有ASD的儿童更有可能发生中耳感染及与中耳炎相关的并发症,这凸显了对该人群进行常规中耳检查以及密切关注听力障碍的重要性。