Steflik D E, McKinney R V, Koth D L
Department of Oral Pathology, School of Dentistry Medical College of Georgia, Augusta.
J Biomed Mater Res. 1989 Aug;23(8):895-909. doi: 10.1002/jbm.820230807.
Identically prepared, screw-type ceramic and titanium endosteal dental implants were inserted in the jaws of adult mongrel dogs for periods of up to 6 months. Sixteen of the 32 total implants supported fixed bridgework. The interface of bone and soft connective tissues with the dental implants was examined by routine and innovative scanning electron microscopic (SEM) techniques using both secondary and backscattered electron imaging. Results demonstrated excellent bone adaptation to both titanium and ceramic implants. Direct adaptation of bone to the upper third of both type implants was observed with only minimal amounts of any intervening fibrous connective tissue. A composite of trabecular bone and fibrous connective tissue was observed in the lower two-thirds of the implants examined. Areas of bone alteration suggestive of osteoid were observed at the thread apicis of some loaded implants. From this investigation we concluded that similar longitudinal tissue responses were generated to one-piece, cylindrical screw-type titanium and alpha alumina oxide ceramic dental implants. Possible bone remodeling was observed at the thread apicis of the loaded implants, an area where occlusal forces may be distributed. We further suggest that one-stage endosteal implants are capable of maintaining a proportional bone-to-implant interface at the apical support region, similar to that suggested to two-stage implant systems.
将同样制备的螺旋型陶瓷和钛质骨内牙种植体植入成年杂种犬的颌骨中，时间长达6个月。32颗种植体中的16颗支持固定桥修复。使用二次电子成像和背散射电子成像的常规及创新扫描电子显微镜（SEM）技术，检查骨和软组织与牙种植体的界面。结果表明，骨对钛和陶瓷种植体均有良好的适应性。观察到骨直接与两种类型种植体的上三分之一部分贴合，其间仅有极少量的纤维结缔组织。在所检查的种植体下三分之二部分观察到骨小梁和纤维结缔组织的复合体。在一些负重种植体的螺纹顶端观察到提示类骨质的骨改变区域。从这项研究中我们得出结论，对于一体式圆柱形螺旋型钛质和α氧化铝陶瓷牙种植体，会产生相似的纵向组织反应。在负重种植体的螺纹顶端观察到可能的骨重塑，该区域可能分布有咬合力。我们进一步表明，单阶段骨内种植体能够在根尖支持区域维持与种植体成比例的骨界面，类似于双阶段种植系统的情况。
