Karki D B, Adhikary K P, Gurung G
Department of Radiology and Imaging, Patan Academy of Health Sciences, Patan, Lalitpur, Nepal.
Nepal Medical Council, Kathmandu, Nepal.
J Nepal Health Res Counc. 2015 May-Aug;13(30):154-9.
The sequel of disc degeneration is one of the leading causes of functional incapacity that leads to chronic disability. The study aims to evaluate the MRI findings of degenerative changes in symptomatic patients.
The study was a retrospective study for the duration of 3 years. Symptomatic patients undergoing MRI of LS spine were included in the study. Patients undergoing MRI for neurological symptoms alone and acute trauma or suspected infection or tumor were excluded from the study. MRI of patients was evaluated for degenerative changes and their sequel. Data was entered in a predesigned proforma and analysis was done with SPSS version 19.0.
A total of 2037 MRIs of LS spine of symptomatic patients were included in the study. Degenerative changes were demonstrated in 1906 (93.8 %) patients, which comprised 1039 (54.5 %) males and 867 (45.4 %) females. Disc bulge along with disc desiccation was the most common degenerative findings noted in 1667 (81.8 %). Disc herniation was seen in 1032(50.6%), neural foraminal stenosis in 1220 (59.8 %), central spinal canal in 1136 (55.8%) and nerve root compression in 650 (31.9%). Disc bulge, neural foraminal stenosis, central spinal canal stenosis was significantly more common in patients older than 40 years. Disc herniation was however significantly more frequent in patients younger than 40 years.
Degenerative changes are common in symptomatic patients and increase in frequency with aging. Disc herniation is however more common in younger patients.
椎间盘退变的后遗症是导致功能丧失进而引发慢性残疾的主要原因之一。本研究旨在评估有症状患者退变改变的磁共振成像（MRI）表现。
本研究为一项为期3年的回顾性研究。纳入接受腰椎MRI检查的有症状患者。仅因神经系统症状、急性创伤、疑似感染或肿瘤而接受MRI检查的患者被排除在研究之外。对患者的MRI进行退变改变及其后遗症评估。数据录入预先设计的表格，并使用SPSS 19.0版进行分析。
本研究共纳入2037例有症状患者的腰椎MRI检查。1906例（93.8%）患者出现退变改变，其中男性1039例（54.5%），女性867例（45.4%）。椎间盘膨出伴椎间盘脱水是最常见的退变表现，见于1667例（81.8%）。观察到椎间盘突出1032例（50.6%），神经孔狭窄1220例（59.8%），中央椎管狭窄1136例（55.8%），神经根受压650例（31.9%）。椎间盘膨出、神经孔狭窄、中央椎管狭窄在40岁以上患者中明显更常见。然而，椎间盘突出在40岁以下患者中明显更频繁。
退变改变在有症状患者中很常见，且随年龄增长而增加。然而，椎间盘突出在年轻患者中更常见。
