Garcia Santiago, Drexel Todd, Bekwelem Wobo, Raveendran Ganesh, Caldwell Emily, Hodgson Lucinda, Wang Qi, Adabag Selcuk, Mahoney Brian, Frascone Ralph, Helmer Gregory, Lick Charles, Conterato Marc, Baran Kenneth, Bart Bradley, Bachour Fouad, Roh Steven, Panetta Carmelo, Stark Randall, Haugland Mark, Mooney Michael, Wesley Keith, Yannopoulos Demetris
Division of Cardiology, Department of Medicine, Minneapolis VA Healthcare System and University of Minnesota School of Medicine, Minneapolis, MN (S.G., S.A.).
Division of Cardiology, Department of Medicine, University of Minnesota School of Medicine, Minneapolis, MN (T.D., W.B., G.R., E.C., L.H., D.Y.).
J Am Heart Assoc. 2016 Jan 7;5(1):e002670. doi: 10.1161/JAHA.115.002670.
In 2013 the Minnesota Resuscitation Consortium developed an organized approach for the management of patients resuscitated from shockable rhythms to gain early access to the cardiac catheterization laboratory (CCL) in the metro area of Minneapolis-St. Paul.
Eleven hospitals with 24/7 percutaneous coronary intervention capabilities agreed to provide early (within 6 hours of arrival at the Emergency Department) access to the CCL with the intention to perform coronary revascularization for outpatients who were successfully resuscitated from ventricular fibrillation/ventricular tachycardia arrest. Other inclusion criteria were age >18 and <76 and presumed cardiac etiology. Patients with other rhythms, known do not resuscitate/do not intubate, noncardiac etiology, significant bleeding, and terminal disease were excluded. The primary outcome was survival to hospital discharge with favorable neurological outcome. Patients (315 out of 331) who were resuscitated from VT/VF and transferred alive to the Emergency Department had complete medical records. Of those, 231 (73.3%) were taken to the CCL per the Minnesota Resuscitation Consortium protocol while 84 (26.6%) were not taken to the CCL (protocol deviations). Overall, 197 (63%) patients survived to hospital discharge with good neurological outcome (cerebral performance category of 1 or 2). Of the patients who followed the Minnesota Resuscitation Consortium protocol, 121 (52%) underwent percutaneous coronary intervention, and 15 (7%) underwent coronary artery bypass graft. In this group, 151 (65%) survived with good neurological outcome, whereas in the group that did not follow the Minnesota Resuscitation Consortium protocol, 46 (55%) survived with good neurological outcome (adjusted odds ratio: 1.99; [1.07-3.72], P=0.03).
Early access to the CCL after cardiac arrest due to a shockable rhythm in a selected group of patients is feasible in a large metropolitan area in the United States and is associated with a 65% survival rate to hospital discharge with a good neurological outcome.
2013年,明尼苏达复苏联盟制定了一种有组织的方法,用于管理从可电击心律复苏的患者,以便在明尼阿波利斯-圣保罗市区的患者能够尽早进入心脏导管实验室(CCL)。
11家具备24/7经皮冠状动脉介入治疗能力的医院同意为成功从室颤/室性心动过速骤停中复苏的门诊患者提供早期(到达急诊科后6小时内)进入CCL的机会,目的是进行冠状动脉血运重建。其他纳入标准为年龄>18岁且<76岁以及推测为心脏病因。排除有其他心律、已知的不复苏/不插管、非心脏病因、严重出血和终末期疾病的患者。主要结局是存活至出院且神经功能结局良好。从室速/室颤中复苏并活着转至急诊科的患者(331例中的315例)有完整的医疗记录。其中,231例(73.3%)按照明尼苏达复苏联盟方案被送往CCL,而84例(26.6%)未被送往CCL(方案偏差)。总体而言,197例(63%)患者存活至出院且神经功能结局良好(脑功能分级为1或2级)。在遵循明尼苏达复苏联盟方案的患者中,121例(52%)接受了经皮冠状动脉介入治疗,15例(7%)接受了冠状动脉旁路移植术。在该组中,151例(65%)存活且神经功能结局良好,而在未遵循明尼苏达复苏联盟方案的组中,46例(55%)存活且神经功能结局良好(调整后的优势比:1.99;[1.07 - 3.72],P = 0.03)。
在美国一个大城市地区,为特定组中因可电击心律导致心脏骤停的患者尽早提供进入CCL的机会是可行的,且与65%的存活至出院率及良好的神经功能结局相关。