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急性早幼粒细胞白血病(AML-M3)患者肺出血和曲霉病的成功管理。

Successful management of pulmonary hemorrhage and aspergillosis in a patient with acute myeloid leukemia (AML-M3).

作者信息

Gunbatar Hulya, Demir Cengiz, Kara Erdal, Esen Ramazan, Sertogullarindan Bunyamin, Asker Selvi

机构信息

Yuzuncu Yil University Medical Faculty, Department of Pulmonary and Critical Care, Turkey.

Yuzuncu Yil University Medical Faculty, Department of Internal Medicine, Haematology, Turkey.

出版信息

Respir Med Case Rep. 2015 Jul 26;16:65-8. doi: 10.1016/j.rmcr.2015.07.003. eCollection 2015.

Abstract

A 35-year-old man presented with a one month history of gingival bleeding. He was diagnosed with Acute Myeloid Leukemia (AML-M3). During treatment he developed alveolar hemorrhage for which he was treated with a steroid. After the steroid treatment he developed a nodule, a cavitary lesion and atelectasia in the left lung. He was treated with voriconazole. After therapy with voriconazole his lesion significantly decreased. This case illustrates the efficacy and safety of antifungal therapy with voriconazole for aspergillosis complicated by AML.

摘要

一名35岁男性,有1个月牙龈出血病史。他被诊断为急性髓系白血病(AML-M3)。治疗期间,他出现了肺泡出血,为此接受了类固醇治疗。类固醇治疗后,他左肺出现了一个结节、一个空洞性病变和肺不张。他接受了伏立康唑治疗。使用伏立康唑治疗后,他的病变明显减轻。该病例说明了伏立康唑抗真菌治疗对并发AML的曲霉病的有效性和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd0/4681978/aa04a4985ee8/gr1.jpg

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